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White blood cell count profiles in multiple sclerosis during attacks before the initiation of acute and chronic treatments

Authors :
Shuhei Nishiyama
Ikumi Kanno
Kazuo Fujihara
Atsushi Hozawa
Mana Kogure
Toshiyuki Takahashi
Tadashi Ishii
Tomohiro Nakamura
Yoshiki Takai
Hiroshi Kuroda
Fumi Itabashi
Rieko Hatanaka
Tatsuro Misu
Kimihiko Kaneko
Juichi Fujimori
Naoki Nakaya
Ichiro Nakashima
Masashi Aoki
Tetsuya Akaishi
Source :
Scientific Reports, Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Publication Year :
2021
Publisher :
Nature Publishing Group UK, 2021.

Abstract

Multiple sclerosis (MS) is a major demyelinating disease of the central nervous system; however, its exact mechanism is unknown. This study aimed to elucidate the profile of white blood cells (WBCs) in the acute phase of an MS attack. Sixty-four patients with MS at the time of diagnosis and 2492 age- and sex-adjusted healthy controls (HCs) were enrolled. Data regarding the blood cell counts were compared between the groups. The total WBC (p p p = 0.0027), and neutrophil (p

Details

Language :
English
ISSN :
20452322
Volume :
11
Database :
OpenAIRE
Journal :
Scientific Reports
Accession number :
edsair.doi.dedup.....837a99373f5ee8ab11c211af54643180