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Curved Beam Computed Tomography based Structural Rigidity Analysis of Bones with Simulated Lytic Defect: A Comparative Study with Finite Element Analysis
- Source :
- Scientific reports, 6:32397. Nature Publishing Group, Scientific Reports, 6, Scientific Reports
- Publication Year :
- 2016
- Publisher :
- Springer Science and Business Media LLC, 2016.
-
Abstract
- In this paper, a CT based structural rigidity analysis (CTRA) method that incorporates bone intrinsic local curvature is introduced to assess the compressive failure load of human femur with simulated lytic defects. The proposed CTRA is based on a three dimensional curved beam theory to obtain critical stresses within the human femur model. To test the proposed method, ten human cadaveric femurs with and without simulated defects were mechanically tested under axial compression to failure. Quantitative computed tomography images were acquired from the samples, and CTRA and finite element analysis were performed to obtain the failure load as well as rigidities in both straight and curved cross sections. Experimental results were compared to the results obtained from FEA and CTRA. The failure loads predicated by curved beam CTRA and FEA are in agreement with experimental results. The results also show that the proposed method is an efficient and reliable method to find both the location and magnitude of failure load. Moreover, the results show that the proposed curved CTRA outperforms the regular straight beam CTRA, which ignores the bone intrinsic curvature and can be used as a useful tool in clinical practices. Beth Israel Deaconess Medical Center Department of Orthopaedic Surgery, the NIH LRP (L30 AR056606) (A.N.), and in part by a NPRP award (NPRP 5-086-2- 031) from the Qatar National Research Fund (a member of the Qatar Foundation)
- Subjects :
- Male
0301 basic medicine
Materials science
Compressive Strength
Finite Element Analysis
0206 medical engineering
02 engineering and technology
Curvature
Article
Weight-Bearing
Stress (mechanics)
Computational biophysics
03 medical and health sciences
Hardness
METIS-320154
Image Interpretation, Computer-Assisted
Bone cancer
medicine
Humans
Femur
Hardness Tests
Quantitative computed tomography
Structural rigidity
Aged
IR-104230
Aged, 80 and over
Multidisciplinary
medicine.diagnostic_test
business.industry
Structural engineering
020601 biomedical engineering
Finite element method
Biomechanical Phenomena
Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]
030104 developmental biology
Autopsy
Stress, Mechanical
Tomography
Tomography, X-Ray Computed
business
Curved beam
Beam (structure)
Subjects
Details
- ISSN :
- 20452322
- Volume :
- 6
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....837a1985015c42dde288623bca733c6f