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Personalized medicine in inflammatory cardiomyopathy
- Source :
- Personalized medicine. 15(2)
- Publication Year :
- 2018
-
Abstract
- Inflammatory cardiomyopathy is the result of persistent myocardial inflammation which can arise from both infectious or noninfectious causes. While most patients with acute myocarditis recover, up to 20% develop inflammatory cardiomyopathy with chronic heart failure. The interaction between host factors and factors of the agent that triggered myocardial inflammation must be considered to fully understand the individual mechanism of disease. Several inflammatory biomarkers, histology, immunohistochemistry, advanced imaging technologies as well as molecular high-throughput sequencing techniques help to identify disease pathways and to establish a comprehensive, individualized treatment approach, which can include anti-inflammatory medication, antiviral drugs and heart failure therapy. This might help to prevent transition from acute inflammation to persistent heart failure and to restore cardiac function.
- Subjects :
- 0301 basic medicine
Cardiac function curve
Cardiomyopathy, Dilated
Myocarditis
Cardiomyopathy
Inflammation
Disease
030204 cardiovascular system & hematology
Bioinformatics
03 medical and health sciences
0302 clinical medicine
medicine
Humans
Precision Medicine
Pharmacology
Heart Failure
business.industry
Mechanism (biology)
Myocardium
General Medicine
medicine.disease
030104 developmental biology
Heart failure
Molecular Medicine
Personalized medicine
medicine.symptom
business
Cardiomyopathies
Biomarkers
Subjects
Details
- ISSN :
- 1744828X
- Volume :
- 15
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Personalized medicine
- Accession number :
- edsair.doi.dedup.....83681886190b560ac5176809c62b92f0