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Characterization of community and hospital Staphylococcus aureus isolates in Southampton, UK
- Source :
- Journal of medical microbiology. 59(Pt 9)
- Publication Year :
- 2010
-
Abstract
- Staphylococcus aureus infections are a burden to healthcare systems. There remains a lack of understanding on the relative contributions of S. aureus infection in the healthcare and community settings. In this study, 59 S. aureus isolates were selected for molecular analysis. The mobile variant staphylococcal cassette chromosome mec type IV was present in both healthcare-associated meticillin-resistant S. aureus (HA-MRSA) and community-associated MRSA (CA-MRSA), as was the Panton–Valentine leukocidin gene. PFGE identified 24 distinct clonal groups whilst multi-locus sequence typing identified 26 different sequence types, including four with new combinations of alleles. This is the first time, to our knowledge, that a selection of CA and HA MSSA and MRSA strains have been subjected to molecular analysis and comparison in the UK. Definitions for CA-MRSA need further debate as the movement of strains between healthcare and community settings is confounding the use of epidemiological definitions.
- Subjects :
- Microbiology (medical)
medicine.medical_specialty
Staphylococcus aureus
Micrococcaceae
Leukocidin
Drug resistance
Staphylococcal infections
medicine.disease_cause
Microbiology
Epidemiology
medicine
Pulsed-field gel electrophoresis
Humans
Typing
Cross Infection
biology
General Medicine
Gene Expression Regulation, Bacterial
biochemical phenomena, metabolism, and nutrition
Staphylococcal Infections
bacterial infections and mycoses
biology.organism_classification
medicine.disease
United Kingdom
Community-Acquired Infections
Subjects
Details
- ISSN :
- 14735644
- Volume :
- 59
- Issue :
- Pt 9
- Database :
- OpenAIRE
- Journal :
- Journal of medical microbiology
- Accession number :
- edsair.doi.dedup.....8360c85817cf8aa7871e7ae506228ff3