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Phylogeny of the Neurohypophysial Hormones
- Source :
- Nature. 216:1037-1038
- Publication Year :
- 1967
- Publisher :
- Springer Science and Business Media LLC, 1967.
-
Abstract
- VERTEBRATE neurohypophysial hormones have a common structural pattern characterized by a chain of nine amino-acid residues with a disulphide bridge connecting the amino-acids in positions 1 and 6. There are usually two hormones in each species, the active principles rarely varying from one species to another within a given class. Thus oxytocin and arginine vasopressin have been chemically identified in five species of mammals belonging to the orders Primates, Artiodactyla, Perissodactyla and Cetacea. Isotocin (Ser4-Ile8-oxytocin) and vasotocin (Arg8-oxytocin) have up to now been isolated from six species of bony fish belonging to the families Gadidae, Scombridae and Cyprinidae. The structural variations which occur between one vertebrate class and another are confined to one or two amino-acid substitutions in positions 3, 4 or 8 (for a review of this subject see ref. 1).
- Subjects :
- Electrophoresis
Paper
Primates
Vasopressin
Vasopressins
Scombridae
Cyprinidae
Vasotocin
Oxytocin
chemistry.chemical_compound
Phylogenetics
biology.animal
Animals
Amino Acids
Perissodactyla
Artiodactyla
Multidisciplinary
biology
Fishes
Vertebrate
Chromatography, Ion Exchange
biology.organism_classification
Biological Evolution
Bony fish
chemistry
Evolutionary biology
Cetacea
Pituitary Hormones, Posterior
hormones, hormone substitutes, and hormone antagonists
Hormone
Subjects
Details
- ISSN :
- 14764687 and 00280836
- Volume :
- 216
- Database :
- OpenAIRE
- Journal :
- Nature
- Accession number :
- edsair.doi.dedup.....8355a6507309248beb26d03f9afbf972