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Preoperative Panel Testing for Hereditary Cancer Syndromes Does Not Significantly Impact Time to Surgery for Newly Diagnosed Breast Cancer Patients Compared with BRCA1/2 Testing
- Source :
- Annals of surgical oncology. 24(10)
- Publication Year :
- 2017
-
Abstract
- This study seeks to determine whether there is a delay in time to surgery in breast cancer patients with panel tests compared with traditional BRCA testing. This study was a retrospective review of women diagnosed with breast cancer who underwent genetic evaluation from our institution’s Genetic Counselor Database from January 2013 to August 2015. Patients were excluded if they were male, clinical information was unavailable, the patient underwent neoadjuvant chemotherapy, had a diagnosis of recurrent breast cancer during time of study, or had postoperative genetics evaluation. Included in the study were 138 patients. The time from diagnosis to surgery for BRCA1/2 tested patients was 43.5 days compared with 51.0 days in the panel group (p = 0.186). Turnaround time for genetic testing decreased during the period studied and was approximately 6 days longer for panel testing than BRCA testing. It took 12.2 days for BRCA results and 18.9 days for the panel results (p
- Subjects :
- Oncology
medicine.medical_specialty
Heterozygote
medicine.medical_treatment
Genetic counseling
Breast Neoplasms
Preoperative care
03 medical and health sciences
0302 clinical medicine
Breast cancer
Surgical oncology
Neoplastic Syndromes, Hereditary
Internal medicine
Preoperative Care
medicine
Humans
Neoplasm Invasiveness
030212 general & internal medicine
Early Detection of Cancer
Genetic testing
Retrospective Studies
BRCA2 Protein
medicine.diagnostic_test
business.industry
BRCA1 Protein
Prophylactic Mastectomy
Retrospective cohort study
Middle Aged
medicine.disease
Prognosis
Surgery
030220 oncology & carcinogenesis
Mutation
Female
business
Mastectomy
Follow-Up Studies
Subjects
Details
- ISSN :
- 15344681
- Volume :
- 24
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- Annals of surgical oncology
- Accession number :
- edsair.doi.dedup.....83332c775002bdf6be6f3042f38b98de