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Severe mucosal hyperplasia of the edentulous maxilla associated with immunosuppressant therapy: A clinical report
- Source :
- The Journal of Prosthetic Dentistry. 72:1-3
- Publication Year :
- 1994
- Publisher :
- Elsevier BV, 1994.
-
Abstract
- c yclosporin i.s a selective immunosuppressant that is used extensively in organ transplant surgery to prevent graft rejection.’ The drug has many unwanted effects,2 but of particular concern to the dental surgeon is the association between chronic use of this drug and gingival overgrowth.3V8 This unwanted effect has been reported in approximately a third of dentate transplant patients taking cyclosporin.8 The prevalence increases to nearly 50 % when both cyclosporin and nifedipine, a dihydropyridine derivative, are used eoncomitantly.8, g Young patients appear to be more susceptible to cyclosporin-induced gingival changes than adults.1° Although gingival overgrowth associated with cyclosporin and the calcium channel blocking agents is well documented, drug-associated overgrowth of masticatory mucosa in edentulous patients is rare. We report such a case in a renal transplant patient.
- Subjects :
- Male
Drug
medicine.medical_specialty
media_common.quotation_subject
Organ transplantation
Nicardipine
Nifedipine
Candidiasis, Oral
medicine
Humans
Jaw, Edentulous
media_common.cataloged_instance
Dental surgeon
Stomatitis
media_common
business.industry
Denture, Complete, Upper
Mouth Mucosa
Dihydropyridine
Mucosal hyperplasia
Middle Aged
Staphylococcal Infections
medicine.disease
Kidney Transplantation
Stomatitis, Denture
Surgery
Masticatory force
Gingival Hyperplasia
Cyclosporine
Oral Surgery
business
medicine.drug
Subjects
Details
- ISSN :
- 00223913
- Volume :
- 72
- Database :
- OpenAIRE
- Journal :
- The Journal of Prosthetic Dentistry
- Accession number :
- edsair.doi.dedup.....831e2378db4cc9d5140111f90d3bd58f