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How lymphocytes add up

Authors :
Asquith, Becca
de Boer, Rob J
Sub Theoretical Biology
Theoretical Biology and Bioinformatics
Medical Research Council (MRC)
Commission of the European Communities
Wellcome Trust
Leukaemia & Lymphoma Research 'Beating Blood Cancers'
Bloodwise (formerly LLR)
Source :
Nature Immunology, 18(1), 12. Nature Publishing Group
Publication Year :
2016
Publisher :
Nature Publishing Group, 2016.

Abstract

A surprising molecular mechanism underlying signal integration and programmed proliferation in adaptive immunity has been identified: the cell-cycle regulator Myc enables a lymphocyte to add up the strength of signals it receives and time its response accordingly.

Details

Language :
English
ISSN :
15292908
Database :
OpenAIRE
Journal :
Nature Immunology, 18(1), 12. Nature Publishing Group
Accession number :
edsair.doi.dedup.....831a7f75d412918ef54cf18d156ce1ab