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Cost-Effectiveness Analysis of Smoking Cessation Interventions in Japan Using a Discrete-Event Simulation
- Source :
- Applied Health Economics and Health Policy
- Publisher :
- Springer Nature
-
Abstract
- Background Smoking cessation medications have been shown to yield higher success rates and sustained abstinence than unassisted quit attempts. In Japan, the treatments available include nicotine replacement therapy (NRT) and varenicline; however, unassisted attempts to quit smoking remain common. Objective The objective of this study was to compare the health and economic consequences in Japan of using pharmacotherapy to support smoking cessation with unassisted attempts and the current mix of strategies used. Methods A discrete-event simulation that models lifetime quitting behaviour and includes multiple quit attempts (MQAs) and relapses was adapted for these analyses. The risk of developing smoking-related diseases is estimated based on the duration of abstinence. Data collected from a survey conducted in Japan were used to determine the interventions selected by smokers initiating a quit attempt and the time between MQAs. Direct and indirect costs are assessed (expressed in 2014 Japanese Yen). Results Using pharmacotherapy (NRT or varenicline) to support quit attempts proved to be dominant when compared with unassisted attempts or the current mix of strategies (most are unassisted). The results of stratified analyses by age imply that smoking cessation improves health outcomes across all generations. Indirect costs due to premature death leading to lost wages are an important component of the total costs, exceeding the direct medical cost estimates. Conclusions Increased utilisation of smoking cessation pharmacotherapy to support quit attempts is predicted to lead to an increase in the number of smokers achieving abstinence, and provide improvements in health outcomes over a lifetime with no additional costs. Electronic supplementary material The online version of this article (doi:10.1007/s40258-015-0204-3) contains supplementary material, which is available to authorized users.
- Subjects :
- Adult
Male
Economics and Econometrics
Adolescent
Cost-Benefit Analysis
medicine.medical_treatment
media_common.quotation_subject
Young Adult
03 medical and health sciences
chemistry.chemical_compound
Indirect costs
0302 clinical medicine
Japan
Humans
Medicine
Original Research Article
030212 general & internal medicine
Varenicline
Aged
media_common
business.industry
030503 health policy & services
Health Policy
Smoking
Advertising
Health Care Costs
General Medicine
Cost-effectiveness analysis
Middle Aged
Abstinence
Nicotine replacement therapy
Tobacco Use Cessation Devices
Quality-adjusted life year
chemistry
behavior and behavior mechanisms
Smoking cessation
Female
Smoking Cessation
Quality-Adjusted Life Years
Tobacco Use Cessation Products
0305 other medical science
business
Demography
Subjects
Details
- Language :
- English
- ISSN :
- 11755652
- Volume :
- 14
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Applied Health Economics and Health Policy
- Accession number :
- edsair.doi.dedup.....830af6639826645676210205ab19cec5
- Full Text :
- https://doi.org/10.1007/s40258-015-0204-3