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Delayed tooth emergence in children infected with human immunodeficiency virus
- Source :
- Oral surgery, oral medicine, oral pathology and oral radiology. 122(4)
- Publication Year :
- 2016
-
Abstract
- Objective There is limited evidence that early deficits in growth might be reflected in tooth emergence in children infected with human immunodeficiency virus (HIV). The purpose of this study was to prospectively evaluate tooth emergence timing between children positive and negative for HIV in the exposed and unexposed groups, respectively. Study Design A longitudinal study of children positive for HIV and HIV-negative household peers, aged 2 to 15 years was conducted between 1993 and 1996. Emergence status was determined for the maxillary and the mandibular permanent first molars and the central and lateral incisors. A multivariable, discrete time, proportional hazards model was fitted to the data. Median age of emergence for each of the six pairs of teeth was calculated using the parameter estimates from the regression model. Results A total of 116 participants (62 HIV positive, 54 HIV negative) completed six examinations over the 36-month study period. Statistical differences in tooth emergence timing were observed for five of the six tooth pairs, with children positive for HIV being less likely to have emergence of the corresponding tooth compared with the children negative for HIV. Age differences for each tooth pair ranged from 0.7 to 1.5 years, with a median emergence age difference of 1.03 years. Conclusions Delayed tooth emergence of the permanent dentition was observed in children with HIV.
- Subjects :
- Molar
Male
Longitudinal study
Adolescent
Tooth eruption
Human immunodeficiency virus (HIV)
Dentistry
HIV Infections
medicine.disease_cause
01 natural sciences
Article
Pathology and Forensic Medicine
Tooth Eruption
010104 statistics & probability
03 medical and health sciences
0302 clinical medicine
stomatognathic system
Medicine
Humans
Radiology, Nuclear Medicine and imaging
Dentistry (miscellaneous)
Longitudinal Studies
Prospective Studies
0101 mathematics
Prospective cohort study
Child
Dentition
Age differences
business.industry
Proportional hazards model
Infant
030206 dentistry
Dentition, Permanent
stomatognathic diseases
Child, Preschool
Surgery
Female
Oral Surgery
business
Subjects
Details
- ISSN :
- 22124411
- Volume :
- 122
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Oral surgery, oral medicine, oral pathology and oral radiology
- Accession number :
- edsair.doi.dedup.....82a060f1dfcdc66f436b0169f23f7439