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Aortic wall thickness in newborns with intrauterine growth restriction
- Source :
- The Lancet. 365:1484-1486
- Publication Year :
- 2005
- Publisher :
- Elsevier BV, 2005.
-
Abstract
- Much epidemiological evidence has linked low birthweight with late cardiovascular risk. We measured aortic wall thickness (a marker of early atherosclerosis) by ultrasonography in 25 newborn babies with intrauterine growth restriction and 25 with normal birthweight. Maximum aortic thicknesses were significantly higher in the babies with intrauterine growth restriction (810 microm [SD 113]) than in those without (743 microm [76], p=0.02), more so after adjustment for birthweight (300 microm/kg [45] vs 199 microm/kg [29], p0.0001). Newborn babies with growth restriction have significant aortic thickening, suggesting that prenatal events might predispose to later cardiovascular risk.
- Subjects :
- medicine.medical_specialty
Arteriosclerosis
Uterus
Intrauterine growth restriction
Risk Factors
Internal medicine
medicine.artery
medicine
Birth Weight
Humans
Aorta, Abdominal
Aorta
Fetal Growth Retardation
business.industry
Infant, Newborn
General Medicine
medicine.disease
Aortic wall
Surgery
medicine.anatomical_structure
Cardiovascular Diseases
In utero
Circulatory system
Cardiology
Tunica Intima
Tunica Media
business
Blood vessel
Artery
Subjects
Details
- ISSN :
- 01406736
- Volume :
- 365
- Database :
- OpenAIRE
- Journal :
- The Lancet
- Accession number :
- edsair.doi.dedup.....8295513265d6b59985a39b8851b5148b
- Full Text :
- https://doi.org/10.1016/s0140-6736(05)66419-7