Resolution of a giant pigment epithelial detachment after treatment with intravitreal bevacizumab

PURPOSE To describe a patient with a giant pigment epithelial detachment (PED) successfully treated with intravitreal bevacizumab. DESIGN Retrospective, observational case report. METHODS The patient's records were reviewed. RESULTS An 81-year-old man with history of age-related macular degeneration was seen on routine follow-up examination with an asymptomatic PED temporal to the macula in the right eye and visual acuity of 20/40. The patient was observed. Ten months later, the patient was found to have decreased vision to 20/80 and massive enlargement of the PED, with extension from the temporal equator into the macula. Optical coherence tomography of the macula showed a PED with overlying intraretinal cysts. The patient was given injections of intravitreal bevacizumab for every 4 months (1.25 mg) with complete resolution of the PED and return to baseline visual acuity of 20/40. CONCLUSION Giant PED secondary to exudative age-related macular degeneration can be successfully treated with intravitreal bevacizumab.