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Do people with rheumatoid arthritis maintain their physical activity level at treatment onset over the first year of methotrexate therapy?
- Source :
- Rheumatology (Oxford, England)
- Publication Year :
- 2021
- Publisher :
- Oxford University Press (OUP), 2021.
-
Abstract
- Objectives To describe how many people with RA reduce their baseline physical activity level over the first year of MTX treatment, and which factors predict this. Methods Data came from the Rheumatoid Arthritis Medication Study (RAMS), a prospective cohort of people with early RA starting MTX. Participants reported demographics and completed questionnaires at baseline, and 6 and 12 months, including reporting the number of days per week they performed ≥20 min of physical activity, coded as none, low (1–3 days) or high (4–7 days). The physical activity levels of participants over 12 months are described. Predictors of stopping physical activity were assessed using multivariable logistic regression. Results In total, 1468 participants were included [median (interquartile range) age 60 (50, 69) years; 957 (65.2%) women]. At baseline, the physical activity levels of the people with RA were: none = 408 (27.8%), low = 518 (35.3%) and high = 542 (36.9%). Eighty percent of participants maintained some physical activity or began physical activity between assessments (baseline to 6 months = 79.3%, 6 months to 12 months = 80.7%). In total, 24.1% of participants reduced physical activity and 11.3% of participants stopped performing physical activity between baseline and 6 months (6 months to 12 months: 22.6% and 10.2%, respectively). Baseline smoking, higher disability and greater socioeconomic deprivation were associated with stopping physical activity. Conclusion Many people with early RA were not performing physical activity when starting MTX, or stopped performing physical activity over the first year of treatment. These people may require interventions to stay active. These interventions need to be mindful of socioeconomic barriers to physical activity participation.
- Subjects :
- Male
rheumatoid arthritis
medicine.medical_specialty
Psychological intervention
physical activity
Logistic regression
Arthritis, Rheumatoid
socioeconomic status
Rheumatology
Interquartile range
Internal medicine
Epidemiology
medicine
Humans
Pharmacology (medical)
Prospective Studies
Prospective cohort study
Socioeconomic status
AcademicSubjects/MED00360
Aged
exercise
business.industry
Middle Aged
Clinical Science
medicine.disease
Physical activity level
Logistic Models
Methotrexate
Antirheumatic Agents
Rheumatoid arthritis
Female
epidemiology
business
Subjects
Details
- ISSN :
- 14620332 and 14620324
- Volume :
- 60
- Database :
- OpenAIRE
- Journal :
- Rheumatology
- Accession number :
- edsair.doi.dedup.....821db593749499177a215a65fc2e71f0