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The combined use of NPWT and instillation using an octenidine based wound rinsing solution: a case study
- Source :
- Journal of Wound Care. 23:590-596
- Publication Year :
- 2014
- Publisher :
- Mark Allen Group, 2014.
-
Abstract
- Effective wound bed preparation is an essential element in the healing of chronic wounds, including pressure ulcers (PUs). Negative pressure wound therapy (NPWT) reduces oedema, stimulates the formation of granulation tissue and helps remove wound exudate. This helps prepare the wound bed for secondary healing, skin grafting or coverage with flaps. Combining NPWT with an instillation phase using an antiseptic (octenidine based) irrigation solution is a novel approach to PU management. Three patients with Category 4 gluteal PUs were treated with NPWT and instillation fluid, following surgical debridement of necrotic tissue. The aim was to achieve optimal wound bed preparation prior to wound closure by local fasciocutaneous flap. The antiseptic efficacy of octenilin wound irrigation solution in microorganism eradication was quantified by in vitro tests simulating real conditions using leg ulcer vacuum exudates. All wounds completely healed after four weeks, and no adverse incidents occurred due to instillation of octenidine. No recurrence of the PU occurred during a one year follow-up. Declaration of interest: The study was performed independently with no external financial support. The authors have no conflicts of interest to declare with regards to the article or its content.
- Subjects :
- Male
medicine.medical_specialty
Nursing (miscellaneous)
Pyridines
medicine.drug_class
medicine.medical_treatment
Combined use
Local fasciocutaneous flap
Antiseptic
Wound bed preparation
Negative-pressure wound therapy
medicine
Humans
Therapeutic Irrigation
Pressure Ulcer
Wound Healing
integumentary system
business.industry
Surgical debridement
Granulation tissue
Surgery
Treatment Outcome
medicine.anatomical_structure
Anesthesia
Anti-Infective Agents, Local
Wound Infection
Buttocks
Skin grafting
Fundamentals and skills
Imines
business
Negative-Pressure Wound Therapy
Subjects
Details
- ISSN :
- 20522916 and 09690700
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- Journal of Wound Care
- Accession number :
- edsair.doi.dedup.....820310265d5a1f627bd47c3dea5efcfb