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Genome-wide copy number variant data for inflammatory bowel disease in a caucasian population
- Source :
- Data in Brief, Vol 25, Iss, Pp-(2019), Data in Brief
- Publication Year :
- 2019
- Publisher :
- Elsevier, 2019.
-
Abstract
- Genome-wide copy-number association studies offer new opportunities to identify the mechanisms underlying complex diseases, including chronic inflammatory, psychiatric disorders and others. We have used genotyping microarrays to analyse the copy-number variants (CNVs) from 243 Caucasian individuals with Inflammatory Bowel Disease (IBD). The CNV data was obtained by using multiple quality control measures and merging the results of three different CNV detection algorithms: PennCNV, iPattern, and QuantiSNP. The final dataset contains 4,402 CNVs detected by two or three algorithms independently with high confidence. This paper provides a detailed description of the data generation and quality control steps. For further interpretation of the data presented in this article, please see the research article entitled 'Copy number variation-based gene set analysis reveals cytokine signalling pathways associated with psychiatric comorbidity in patients with inflammatory bowel disease'.
- Subjects :
- 0303 health sciences
Multidisciplinary
business.industry
Computational biology
medicine.disease
lcsh:Computer applications to medicine. Medical informatics
Genome
Inflammatory bowel disease
03 medical and health sciences
0302 clinical medicine
Biochemistry, Genetics and Molecular Biology
Medicine
lcsh:R858-859.7
In patient
Copy-number variation
DNA microarray
business
Caucasian population
lcsh:Science (General)
Genotyping
030217 neurology & neurosurgery
030304 developmental biology
Genetic association
lcsh:Q1-390
Subjects
Details
- Language :
- English
- ISSN :
- 23523409
- Volume :
- 25
- Database :
- OpenAIRE
- Journal :
- Data in Brief
- Accession number :
- edsair.doi.dedup.....81defdc6c8d28424dfdbe2b13877c24e