Synthesis and antiproliferative activity of 6BrCaQ-TPP conjugates for targeting the mitochondrial heat shock protein TRAP1

Authors :: Clelia Mathieu
Quentin Chamayou
Thi Thanh Hyen Luong
Delphine Naud
Florence Mahuteau-Betzer
Mouad Alami
Elias Fattal
Samir Messaoudi
Juliette Vergnaud-Gauduchon
Source :: European journal of medicinal chemistry. 229
Publication Year :: 2021
Abstract: A series of 6BrCaQ-C

Subjects :: Pharmacology
Membrane Potential, Mitochondrial
Organic Chemistry
Antineoplastic Agents
General Medicine
Quinolones
Mitochondria
Structure-Activity Relationship
Organophosphorus Compounds
Cell Line, Tumor
Drug Discovery
Humans
HSP90 Heat-Shock Proteins
Cell Proliferation

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