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International trends in antipsychotic use
- Source :
- European Neuropsychopharmacology, 27(10), 1064-1076. ELSEVIER SCIENCE BV
- Publication Year :
- 2017
- Publisher :
- ELSEVIER SCIENCE BV, 2017.
-
Abstract
- The objective of this study was to assess international trends in antipsychotic use, using a standardised methodology. A repeated cross-sectional design was applied to data extracts from the years 2005 to 2014 from 16 countries worldwide. During the study period, the overall prevalence of antipsychotic use increased in 10 of the 16 studied countries. In 2014, the overall prevalence of antipsychotic use was highest in Taiwan (78.2/1000 persons), and lowest in Colombia (3.2/1000). In children and adolescents (0-19 years), antipsychotic use ranged from 0.5/1000 (Lithuania) to 30.8/1000 (Taiwan). In adults (20-64 years), the range was 2.8/1000 (Colombia) to 78.9/1000 (publicly insured US population), and in older adults (65+ years), antipsychotic use ranged from 19.0/1000 (Colombia) to 149.0/1000 (Taiwan). Atypical antipsychotic use increased in all populations (range of atypical/typical ratio: 0.7 (Taiwan) to 6.1 (New Zealand, Australia)). Quetiapine, risperidone, and olanzapine were most frequently prescribed. Prevalence and patterns of antipsychotic use varied markedly between countries. In the majority of populations, antipsychotic utilisation and especially the use of atypical antipsychotics increased over time. The high rates of antipsychotic prescriptions in older adults and in youths in some countries merit further investigation and systematic pharmacoepidemiologic monitoring.
- Subjects :
- Olanzapine
Internationality
Cross-sectional study
Antipsychotic agents
medicine.medical_treatment
CHILDREN
NATIONAL TRENDS
0302 clinical medicine
ADOLESCENTS
Pharmacology (medical)
Child
education.field_of_study
Age Factors
BIPOLAR DISORDER
Pharmacoepidemiology
Middle Aged
SAFETY WARNINGS
PREVALENCE
Psychiatry and Mental health
Neurology
DRUG USE
Child, Preschool
medicine.drug
Adult
medicine.medical_specialty
Adolescent
medicine.drug_class
Population
Atypical antipsychotic
03 medical and health sciences
Young Adult
Sex Factors
Drug Therapy
DISEASE PATTERNS
medicine
Humans
ANTIDEPRESSANT USE
education
Antipsychotic
Psychiatry
Biological Psychiatry
Aged
Pharmacology
Risperidone
business.industry
Infant, Newborn
Infant
030227 psychiatry
Minors
Cross-Sectional Studies
Quetiapine
MENTAL-HEALTH-CARE
Neurology (clinical)
business
030217 neurology & neurosurgery
Demography
Subjects
Details
- Language :
- English
- ISSN :
- 18737862 and 0924977X
- Volume :
- 27
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- European Neuropsychopharmacology
- Accession number :
- edsair.doi.dedup.....81c27086b397a7b5a74321d3c2b8e239
- Full Text :
- https://doi.org/10.1016/j.euroneuro.2017.07.001