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International trends in antipsychotic use

Authors :
Corinne Zara Yahni
Koji Kawakami
Yu-Chiau Shyu
Svetlana Skurtveit
Takuya Kinoshita
Lise Aagaard
Jorge Enrique Machado-Alba
Izumi Sato
Helga Zoega
Sallie-Anne Pearson
Kari Furu
Catharina C. M. Schuiling-Veninga
Christian Bachmann
Falk Hoffmann
Johan Reutfors
Melisa Litchfield
Miquel Bernardo
Soffy C. López
Manuel Enrique Machado-Duque
Luuk J. Kalverdijk
Helle Kieler
Anna Coma Fusté
Prasad S. Nishtala
Lena Brandt
Mufaddal Mahesri
Krista F. Huybrechts
Liang-Jen Wang
Kristina Garuoliene
Hélène Verdoux
Oskar Halfdanarson
Leena K. Saastamoinen
PharmacoTherapy, -Epidemiology and -Economics
Source :
European Neuropsychopharmacology, 27(10), 1064-1076. ELSEVIER SCIENCE BV
Publication Year :
2017
Publisher :
ELSEVIER SCIENCE BV, 2017.

Abstract

The objective of this study was to assess international trends in antipsychotic use, using a standardised methodology. A repeated cross-sectional design was applied to data extracts from the years 2005 to 2014 from 16 countries worldwide. During the study period, the overall prevalence of antipsychotic use increased in 10 of the 16 studied countries. In 2014, the overall prevalence of antipsychotic use was highest in Taiwan (78.2/1000 persons), and lowest in Colombia (3.2/1000). In children and adolescents (0-19 years), antipsychotic use ranged from 0.5/1000 (Lithuania) to 30.8/1000 (Taiwan). In adults (20-64 years), the range was 2.8/1000 (Colombia) to 78.9/1000 (publicly insured US population), and in older adults (65+ years), antipsychotic use ranged from 19.0/1000 (Colombia) to 149.0/1000 (Taiwan). Atypical antipsychotic use increased in all populations (range of atypical/typical ratio: 0.7 (Taiwan) to 6.1 (New Zealand, Australia)). Quetiapine, risperidone, and olanzapine were most frequently prescribed. Prevalence and patterns of antipsychotic use varied markedly between countries. In the majority of populations, antipsychotic utilisation and especially the use of atypical antipsychotics increased over time. The high rates of antipsychotic prescriptions in older adults and in youths in some countries merit further investigation and systematic pharmacoepidemiologic monitoring.

Details

Language :
English
ISSN :
18737862 and 0924977X
Volume :
27
Issue :
10
Database :
OpenAIRE
Journal :
European Neuropsychopharmacology
Accession number :
edsair.doi.dedup.....81c27086b397a7b5a74321d3c2b8e239
Full Text :
https://doi.org/10.1016/j.euroneuro.2017.07.001