Back to Search
Start Over
Resective Surgery for Double Epileptic Foci Overlapping Anterior and Posterior Language Areas: A Case of Epilepsy With Tuberous Sclerosis Complex
- Source :
- Frontiers in Neurology, Vol 9 (2018), Frontiers in Neurology
- Publication Year :
- 2018
- Publisher :
- Frontiers Media SA, 2018.
-
Abstract
- Tuberous sclerosis complex is a genetic systematic disorder characterized by hamartomas in multiple organs. Cortical tubers, the hamartomas in the cerebrum, cause multifocal refractory seizures. In certain cases, epileptic foci potentially involve language areas, and hence, extra- and intraoperative cortical mapping can help identify anterior and posterior areas, thus avoiding postsurgical language impairment. We report on a 21-year-old female with tuberous sclerosis complex experiencing refractory partial seizures due to two epileptic foci in the left hemisphere overlapping anterior and posterior language areas. To completely evaluate both language areas, we performed stepwise resections beginning from the anterior to the posterior epileptic focus. Although the patient presented with expressive aphasia following anterior resection, it was possible to conduct language tests during every resection. Postoperatively, she presented with expressive aphasia, comprehension deficits, left-right disorientations, and arithmetic deficits. The language dysfunctions almost disappeared at 5 weeks after the surgery, and were completely resolved at 6 months after surgery. At postoperative 9 months, she was free from seizures.
- Subjects :
- Cortical tubers
medicine.medical_specialty
language area
Case Report
Wernicke’s area
tuberous sclerosis complex
Wernicke's area
Lateralization of brain function
lcsh:RC346-429
03 medical and health sciences
Tuberous sclerosis
Epilepsy
0302 clinical medicine
Broca’s area
Medicine
Epilepsy surgery
030212 general & internal medicine
Broca's area
lcsh:Neurology. Diseases of the nervous system
business.industry
medicine.disease
Surgery
awake surgery
Expressive aphasia
language mapping
Neurology
epilepsy surgery
Neurology (clinical)
business
030217 neurology & neurosurgery
Neuroscience
Subjects
Details
- Language :
- English
- ISSN :
- 16642295
- Volume :
- 9
- Database :
- OpenAIRE
- Journal :
- Frontiers in Neurology
- Accession number :
- edsair.doi.dedup.....81b7424cfadbfdaa24c30ffcdbf98f91
- Full Text :
- https://doi.org/10.3389/fneur.2018.00343