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Dynapenia Rather Than Sarcopenia Is Associated with Metabolic Syndrome in Patients with Chronic Liver Diseases
- Source :
- Diagnostics, Volume 11, Issue 7, Diagnostics, Vol 11, Iss 1262, p 1262 (2021)
- Publication Year :
- 2021
- Publisher :
- MDPI AG, 2021.
-
Abstract
- We aimed to examine the association between sarcopenia-related factors and metabolic syndrome (Met-S) in patients with chronic liver diseases (CLDs, n = 582, average age = 59.5 years, 290 males, 168 liver cirrhosis cases). Met-S was determined based on the Japanese criteria. Sarcopenia was determined based on grip strength (GS) and skeletal muscle index (SMI) by bioelectrical impedance analysis. Our cohort was divided into the four groups: (A) sarcopenia (n = 44), (B) dynapenia (n = 45), (C) presarcopenia (n = 112), and (D) the control (n = 381). Impacts of GS and SMI on Met-S were investigated. In males, waist circumference (WC) ≥ 85 cm was observed in 199 patients (68.6%), while in females, WC ≥ 90 cm was observed in 94 patients (32.2%). Met-S was identified in 109 patients (18.7%). The proportion of Met-S in the group A, B, C and D were 18.2%, 48.9%, 8.0%, and 18.4% (A vs. B, p = 0.0033<br />B vs. C, p &lt<br />0.0001<br />C vs. D, p = 0.0081<br />A vs. C, p = 0.0867<br />A vs. D, p = 1.000, B vs. D, p &lt<br />overall p value &lt<br />0.0001). Multivariate analysis revealed that age, gender, and group B (dynapenia) were significant factors linked to the presence of Met-S. In conclusion, dynapenia rather than sarcopenia is associated with Met-S in CLD patients.
- Subjects :
- Medicine (General)
medicine.medical_specialty
Cirrhosis
Waist
Clinical Biochemistry
030209 endocrinology & metabolism
Chronic liver disease
Gastroenterology
Article
metabolic syndrome
sarcopenia
03 medical and health sciences
Grip strength
R5-920
0302 clinical medicine
Internal medicine
medicine
business.industry
chronic liver disease
dynapenia
medicine.disease
Sarcopenia
Cohort
030211 gastroenterology & hepatology
Metabolic syndrome
business
human activities
Bioelectrical impedance analysis
Subjects
Details
- ISSN :
- 20754418
- Volume :
- 11
- Database :
- OpenAIRE
- Journal :
- Diagnostics
- Accession number :
- edsair.doi.dedup.....817d848911df5a5f8a019f5f10e1f22d