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Percentile curves for the knee injury and osteoarthritis outcome score in the middle-aged Dutch population
- Source :
- Loef, M, Kroon, F P B, Böhringer, S, Roos, E M, Rosendaal, F R & Kloppenburg, M 2020, ' Percentile curves for the knee injury and osteoarthritis outcome score in the middle-aged Dutch population ', Osteoarthritis and Cartilage, vol. 28, no. 8, pp. 1046-1054 . https://doi.org/10.1016/j.joca.2020.03.014, Loef, M, Kroon, F P, Bohringer, S, Roos, E M, Rosendaal, F R & Kloppenburg, M 2020, ' Percentile curves for the knee injury and osteoarthritis outcome score in the middle-aged dutch population ', Osteoarthritis and Cartilage, bind 28, nr. Suppl. 1, s. S369 . https://doi.org/10.1016/j.joca.2020.02.576, Osteoarthritis and Cartilage, 28(8), 1046-1054. ELSEVIER SCI LTD
- Publication Year :
- 2020
-
Abstract
- Objective: To improve the interpretation of the Knee injury and Osteoarthritis Outcome Score (KOOS) in individual patients, we explored associations with age, sex, BMI, history of knee injury and presence of clinical knee osteoarthritis, and developed percentile curves.Methods: We used cross-sectional data of middle-aged individuals from the population-based Netherlands Epidemiology of Obesity (NEO) study. Clinical knee osteoarthritis was defined using the ACR classification criteria. KOOS scores were handled according to the manual (zero = extreme problems, 100 = no problems). Patient characteristics associated with KOOS were explored using ordered logistic regression, and sex and body mass index (BMI)-specific percentile curves were developed using quantile regression with fractional polynomials. The curves were applied as a benchmark for comparison of KOOS scores of participants with knee osteoarthritis and comorbidities.Results: The population consisted of 6,643 participants (56% women, mean (SD) age 56(6) years). Population-based KOOS subscale scores (median; interquartile range) near optimum: pain (100;94-100), symptoms (96;86-100), ADL function (100;96-100), sport/recreation function (100;80-100), quality of life (100;75-100). Worse KOOS scores were observed in women and in participants with higher BMI. Clinical knee osteoarthritis was defined in 15% of participants, and was, in comparison to other patient characteristics, associated with the highest odds of worse KOOS scores. Furthermore, presence of any comorbidity and cardiovascular disease specifically, was associated with worse KOOS scores, particularly in women.Conclusions: In the middle-aged Dutch population KOOS scores were generally good, but worse in women and with higher BMI. These percentile curves may be used as benchmarks in research and clinical practice. (c) 2020 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.
- Subjects :
- 0301 basic medicine
Percentile
medicine.medical_specialty
Knee Joint
Population
Biomedical Engineering
Pain
Injury
Knee Injuries
Osteoarthritis
Body Mass Index
03 medical and health sciences
Sex Factors
0302 clinical medicine
Rheumatology
Quality of life
Reference Values
Interquartile range
Surveys and Questionnaires
Activities of Daily Living
Humans
Medicine
Orthopedics and Sports Medicine
Knee
Patient Reported Outcome Measures
education
Netherlands
Complaints
030203 arthritis & rheumatology
education.field_of_study
business.industry
KOOS
Benchmarks
Middle Aged
Osteoarthritis, Knee
medicine.disease
Comorbidity
Cross-Sectional Studies
Logistic Models
030104 developmental biology
Quality of Life
Physical therapy
Ordered logit
Percentile curves
business
Body mass index
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Loef, M, Kroon, F P B, Böhringer, S, Roos, E M, Rosendaal, F R & Kloppenburg, M 2020, ' Percentile curves for the knee injury and osteoarthritis outcome score in the middle-aged Dutch population ', Osteoarthritis and Cartilage, vol. 28, no. 8, pp. 1046-1054 . https://doi.org/10.1016/j.joca.2020.03.014, Loef, M, Kroon, F P, Bohringer, S, Roos, E M, Rosendaal, F R & Kloppenburg, M 2020, ' Percentile curves for the knee injury and osteoarthritis outcome score in the middle-aged dutch population ', Osteoarthritis and Cartilage, bind 28, nr. Suppl. 1, s. S369 . https://doi.org/10.1016/j.joca.2020.02.576, Osteoarthritis and Cartilage, 28(8), 1046-1054. ELSEVIER SCI LTD
- Accession number :
- edsair.doi.dedup.....8147b7e6010bd7fe3853ffbca4d64a4d