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Oncologic emergency in patients with skeletal metastasis of unknown primary
- Source :
- Acute Medicine & Surgery, Acute Medicine & Surgery, Vol 8, Iss 1, Pp n/a-n/a (2021)
- Publication Year :
- 2020
-
Abstract
- Oncologic emergency (OE) was observed in as many as 36% of patients with skeletal metastasis from unknown primary malignancy in this study. Delirium and respiratory failure were only two significant prognostic risk factors, which suggest that many of the OEs in untreated advanced cancer patients have probable chance to resolve. Early detection followed by appropriate treatment of such OEs is recommended.<br />Aim Patients with skeletal metastasis from prediagnosed primary malignancy sometimes have concurrent oncologic emergency (OE) during the first visit. This study aims to investigate the types of OEs and treatment outcome in such patients. Methods We have experienced 359 patients with skeletal metastasis from unknown primary malignancy. Among them, 130 patients required immediate admission for OE treatment (OE group), 229 patients had no OE and did not required immediate admission (non‐OE group). Results The recognized types of OE were spinal cord compression in 60 patients, cancer pain in 30, hypercalcemia in 19, delirium in 16, deep vein thrombosis in 13, acute renal failure in 6, respiratory failure in 3, gastrointestinal hemorrhage in 3, and disseminated intravascular coagulation in 1. The overall 5‐year survival rates were 28% and 37% in the OE and non‐OE groups, respectively (P
- Subjects :
- medicine.medical_specialty
Oncologic emergency
Deep vein
skeletal metastasis
Malignancy
Gastroenterology
03 medical and health sciences
0302 clinical medicine
Spinal cord compression
Internal medicine
medicine
unknown primary malignancy
030212 general & internal medicine
business.industry
RC86-88.9
Hazard ratio
General Engineering
Medical emergencies. Critical care. Intensive care. First aid
Original Articles
medicine.disease
Thrombosis
Confidence interval
medicine.anatomical_structure
Respiratory failure
030220 oncology & carcinogenesis
Delirium
Original Article
prognosis
medicine.symptom
business
Subjects
Details
- ISSN :
- 20528817
- Volume :
- 8
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Acute medicinesurgery
- Accession number :
- edsair.doi.dedup.....811210c260dea736c53e4005c3aacdc2