Longitudinal Intra- and Inter-individual variation in T-cell subsets of HIV-infected and uninfected men participating in the LA Multi-Center AIDS Cohort Study

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To assess the intra-individual and inter-individuals biological variation and the effect of aging on lymphocyte T-cells subsets. We assessed lymphocyte phenotypes (CD3+, CD4+, and CD8+ T-cells) in 89 HIV-1-infected and 88 uninfected white non-Hispanic men every 6 months, to examine the biological variation for those measurements, and the average change in lymphocyte phenotype over 34 years. The markers showed significant intra-individuality in HIV-infected and uninfected individuals with index of individuality of