Back to Search
Start Over
Safety and Efficacy of an Aortic Arch Stent Graft with Window-Shaped Fenestration for Supra-Aortic Arch Vessels: an Experimental Study in Swine
- Source :
- Korean Circulation Journal
- Publication Year :
- 2016
-
Abstract
- Background and objectives Thoracic endovascular aortic repair exhibits limitations in cases where the aortic pathology involves the aortic arch. We had already developed a fenestrated aortic stent graft (FASG) with a preloaded catheter for aortic pathology involving the aortic arch. FASG was suitable for elective cases. Materials and methods An aortic arch stent graft with a window-shaped fenestration (FASG-W) for supra-aortic arch vessels is suitable for emergent cases. This study aims to test a FASG-W for supra-aortic arch vessels and to perform a preclinical study in swine to evaluate the safety and efficacy of this device. Six FASG-Ws with 1 preloaded catheter were advanced through the iliac artery in 6 swine. The presence of endoleak and the patency and deformity of the grafts were examined with computed tomography (CT) at 4 weeks postoperatively. A postmortem examination was performed at 8 weeks. The mean procedure time for FASG-W was 27.15±4.02 minutes. The mean time for the selection of the right carotid artery was 5.72±0.72 minutes. Results Major adverse events were not observed in any of the 6 pigs who survived for 8 weeks. For the FASG-W, no endoleaks, no disconnection, and no occlusion of the stent grafts were observed in the CT findings or the postmortem gross findings. Conclusion The procedure with the FASG-W was able to be performed safely in a relatively short procedure time and involved an easy technique. The FASG-W was found to be safe and convenient for use in this preclinical study of swine.
- Subjects :
- Aortic arch
medicine.medical_specialty
medicine.medical_treatment
030204 cardiovascular system & hematology
Aortic diseases
Thoracic aortic aneurysm
03 medical and health sciences
0302 clinical medicine
Aneurysm
medicine.artery
Occlusion
Internal Medicine
medicine
Deformity
030212 general & internal medicine
Arch
business.industry
Stent
Aneurysm, thoracic aortic
medicine.disease
Catheter
cardiovascular system
Animal experimentation
Original Article
Stents
Radiology
medicine.symptom
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 17385520
- Volume :
- 47
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Korean circulation journal
- Accession number :
- edsair.doi.dedup.....80ee3a353c7e5682ab9d7612fab3f429