Back to Search
Start Over
Mood instability in bipolar disorder type I versus type II-continuous daily electronic self-monitoring of illness activity using smartphones
- Source :
- Journal of Affective Disorders. 186:342-349
- Publication Year :
- 2015
- Publisher :
- Elsevier BV, 2015.
-
Abstract
- Background A substantial proportion of patients with bipolar disorder remain symptomatic during inter-episode periods, and mood instability is associated with high risk of relapse and hospitalization. Few studies have investigated long-term daily illness activity and none has compared bipolar type I and II using daily data. The objectives were to investigate differences in daily illness activity between bipolar disorder type I and II. Methods A smartphone-based system for self-monitoring was developed. A total of 33 patients treated in a mood clinic used the system for daily self-monitoring during a median period of 310 days [IQR 189; 437]. Data presented summarize over 8500 observations. Results Patients with bipolar disorder type II ( n =20), compared to patients with bipolar disorder type I ( n =13), experienced a significant lower mean level of mood on a scale from −3; +3 (−0.54 (95% CI: −0.74; −0.35) versus −0.19 (95% CI: −0.35; −0.02), p =0.02), less time euthymic (51.0% (95% CI: 36.4; 65.7) versus 74.5% (95% CI: 62.4; 86.7), p =0.03) and a higher proportion of time with depressive symptoms (45.1% (95% CI: 30.6; 59.5) versus 18.8% (95% CI: 6.9; 30.7), p =0.01). The proportion of time spent with (hypo)manic symptoms did not differ (2.7% (95% CI: 0.1; 5.5) versus 5.5% (95% CI: 3.1; 7.8), p =0.17). Limitations Patients received different types, doses and combinations of psychopharmacological treatment. Conclusion Euthymia was obtained for a substantial proportion of time in patients with bipolar disorder type I, but despite on-going treatment only for half of the time for patients with bipolar disorder type II. This emphasizes the need for improving treatment strategies for bipolar disorder type II.
- Subjects :
- Adult
Male
Self-Assessment
medicine.medical_specialty
Bipolar Disorder
Mood instability
Diagnostic Self Evaluation
Internal medicine
medicine
Humans
In patient
Bipolar disorder
Relapse risk
Psychiatry
Depression (differential diagnoses)
Depressive symptoms
Depression
Cyclothymic Disorder
Middle Aged
medicine.disease
Affect
Psychiatry and Mental health
Clinical Psychology
Mood
Female
Smartphone
Psychology
Subjects
Details
- ISSN :
- 01650327
- Volume :
- 186
- Database :
- OpenAIRE
- Journal :
- Journal of Affective Disorders
- Accession number :
- edsair.doi.dedup.....80e5a90c8dc486309043cce7e7595c00