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Protein-altering germline mutations implicate novel genes related to lung cancer development
- Source :
- Scopus, RUO. Repositorio Institucional de la Universidad de Oviedo, instname, RUO: Repositorio Institucional de la Universidad de Oviedo, Universidad de Oviedo (UNIOVI), Nature Communications, Ji, X, Mukherjee, S, Landi, M T, Bosse, Y, Joubert, P, Zhu, D, Gorlov, I, Xiao, X, Han, Y, Gorlova, O, Hung, R J, Brhane, Y, Carreras-Torres, R, Christiani, D C, Caporaso, N, Johansson, M, Liu, G, Bojesen, S E, Le Marchand, L, Albanes, D, Bickeböller, H, Aldrich, M C, Bush, W S, Tardon, A, Rennert, G, Chen, C, Byun, J, Dragnev, K H, Field, J K, Kiemeney, L F, Lazarus, P, Zienolddiny, S, Lam, S, Schabath, M B, Andrew, A S, Bertazzi, P A, Pesatori, A C, Diao, N, Su, L, Song, L, Zhang, R, Leighl, N, Johansen, J S, Mellemgaard, A, Saliba, W, Haiman, C, Wilkens, L, Fernandez-Somoano, A, Fernandez-Tardon, G, Heijden, E H F M V D, Kim, J H, Davies, M P A, Marcus, M W, Brunnström, H, Manjer, J, Melander, O, Muller, D C, Overvad, K, Trichopoulou, A, Tumino, R, Goodman, G E, Cox, A, Taylor, F, Woll, P, Wichmann, E, Muley, T, Risch, A, Rosenberger, A, Grankvist, K, Johansson, M, Shepherd, F, Tsao, M S, Arnold, S M, Haura, E B, Bolca, C, Holcatova, I, Janout, V, Kontic, M, Lissowska, J, Mukeria, A, Ognjanovic, S, Orlowski, T M, Scelo, G, Swiatkowska, B, Zaridze, D, Bakke, P, Skaug, V, Butler, L M, Offit, K, Srinivasan, P, Bandlamudi, C, Hellmann, M D, Solit, D B, Robson, M E, Rudin, C M, Stadler, Z K, Taylor, B S, Berger, M F, Houlston, R, McLaughlin, J, Stevens, V, Nickle, D C, Obeidat, M, Timens, W, Artigas, M S, Shete, S, Brenner, H, Chanock, S, Brennan, P, McKay, J D & Amos, C I 2020, ' Protein-altering germline mutations implicate novel genes related to lung cancer development ', Nature Communications, vol. 11, no. 1, 2220 . https://doi.org/10.1038/s41467-020-15905-6, NATURE COMMUNICATIONS, Nature Communications, 11, Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020), Nat. Commun. 11:2220 (2020), Nature Communications, 11, 1, Nature Communications, 11(1):2220. Nature Publishing Group
- Publication Year :
- 2020
- Publisher :
- Umeå universitet, Klinisk kemi, 2020.
-
Abstract
- The CAPUA study was supported by FIS-FEDER/Spain grant numbers FIS-01/310, FIS-PI03-0365, and FIS-07-BI060604, FICYT/Asturias grant numbers FICYT PB02-67 and FICYT IB09-133, and the University Institute of Oncology (IUOPA), of the University of Oviedo and the Ciber de Epidemiologia y Salud Pública. CIBERESP, SPAIN (...)<br />Ji, X., Mukherjee, S., Landi, M.T., Bosse, Y., Joubert, P., Zhu, D., Gorlov, I., Xiao, X., Han, Y., Gorlova, O., Hung, R.J., Brhane, Y., Carreras-Torres, R., Christiani, D.C., Caporaso, N., Johansson, M., Liu, G., Bojesen, S.E., Le Marchand, L., Albanes, D., Bickeböller, H., Aldrich, M.C., Bush, W.S., Tardon, A., Rennert, G., Chen, C., Byun, J., Dragnev, K.H., Field, J.K., Kiemeney, L.F., Lazarus, P., Zienolddiny, S., Lam, S., Schabath, M.B., Andrew, A.S., Bertazzi, P.A., Pesatori, A.C., Diao, N., Su, L., Song, L., Zhang, R., Leighl, N., Johansen, J.S., Mellemgaard, A., Saliba, W., Haiman, C., Wilkens, L., Fernandez-Somoano, A., Fernandez-Tardon, G., Heijden, E.H.F.M., Kim, J.H., Davies, M.P.A., Marcus, M.W., Brunnström, H., Manjer, J., Melander, O., Muller, D.C., Overvad, K., Trichopoulou, A., Tumino, R., Goodman, G.E., Cox, A., Taylor, F., Woll, P., Wichmann, E., Muley, T., Risch, A., Rosenberger, A., Grankvist, K., Johansson, M., Shepherd, F., Tsao, M.-S., Arnold, S.M., Haura, E.B., Bolca, C., Holcatova, I., Janout, V., Kontic, M., Lissowska, J., Mukeria, A., Ognjanovic, S., Orlowski, T.M., Scelo, G., Swiatkowska, B., Zaridze, D., Bakke, P., Skaug, V., Butler, L.M., Offit, K., Srinivasan, P., Bandlamudi, C., Hellmann, M.D., Solit, D.B., Robson, M.E., Rudin, C.M., Stadler, Z.K., Taylor, B.S., Berger, M.F., Houlston, R., McLaughlin, J., Stevens, V., Nickle, D.C., Obeidat, M., Timens, W., Artigas, M.S., Shete, S., Brenner, H., Chanock, S., Brennan, P., McKay, J.D., Amos, C.I.
- Subjects :
- 0301 basic medicine
Male
Candidate gene
Lung Neoplasms
Genotyping Techniques
General Physics and Astronomy
Ataxia Telangiectasia Mutated Proteins
Germline
Loss of heterozygosity
0302 clinical medicine
Risk Factors
Databases, Genetic
Odds Ratio
RNA-Seq
lcsh:Science
Oligonucleotide Array Sequence Analysis
Cancer
Genetics
Multidisciplinary
respiratory system
Middle Aged
Pedigree
Urological cancers Radboud Institute for Health Sciences [Radboudumc 15]
030220 oncology & carcinogenesis
Female
Medical Genetics
Rare cancers Radboud Institute for Health Sciences [Radboudumc 9]
Heterozygote
Science
Mutation, Missense
Biology
Adenocarcinoma
General Biochemistry, Genetics and Molecular Biology
White People
Article
03 medical and health sciences
All institutes and research themes of the Radboud University Medical Center
Germline mutation
medicine
Humans
Genetic Predisposition to Disease
Allele
Lung cancer
Alleles
Germ-Line Mutation
Aged
Medicinsk genetik
General Chemistry
medicine.disease
Lung cancer susceptibility
Computational biology and bioinformatics
030104 developmental biology
Jews
lcsh:Q
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Database :
- OpenAIRE
- Journal :
- Scopus, RUO. Repositorio Institucional de la Universidad de Oviedo, instname, RUO: Repositorio Institucional de la Universidad de Oviedo, Universidad de Oviedo (UNIOVI), Nature Communications, Ji, X, Mukherjee, S, Landi, M T, Bosse, Y, Joubert, P, Zhu, D, Gorlov, I, Xiao, X, Han, Y, Gorlova, O, Hung, R J, Brhane, Y, Carreras-Torres, R, Christiani, D C, Caporaso, N, Johansson, M, Liu, G, Bojesen, S E, Le Marchand, L, Albanes, D, Bickeböller, H, Aldrich, M C, Bush, W S, Tardon, A, Rennert, G, Chen, C, Byun, J, Dragnev, K H, Field, J K, Kiemeney, L F, Lazarus, P, Zienolddiny, S, Lam, S, Schabath, M B, Andrew, A S, Bertazzi, P A, Pesatori, A C, Diao, N, Su, L, Song, L, Zhang, R, Leighl, N, Johansen, J S, Mellemgaard, A, Saliba, W, Haiman, C, Wilkens, L, Fernandez-Somoano, A, Fernandez-Tardon, G, Heijden, E H F M V D, Kim, J H, Davies, M P A, Marcus, M W, Brunnström, H, Manjer, J, Melander, O, Muller, D C, Overvad, K, Trichopoulou, A, Tumino, R, Goodman, G E, Cox, A, Taylor, F, Woll, P, Wichmann, E, Muley, T, Risch, A, Rosenberger, A, Grankvist, K, Johansson, M, Shepherd, F, Tsao, M S, Arnold, S M, Haura, E B, Bolca, C, Holcatova, I, Janout, V, Kontic, M, Lissowska, J, Mukeria, A, Ognjanovic, S, Orlowski, T M, Scelo, G, Swiatkowska, B, Zaridze, D, Bakke, P, Skaug, V, Butler, L M, Offit, K, Srinivasan, P, Bandlamudi, C, Hellmann, M D, Solit, D B, Robson, M E, Rudin, C M, Stadler, Z K, Taylor, B S, Berger, M F, Houlston, R, McLaughlin, J, Stevens, V, Nickle, D C, Obeidat, M, Timens, W, Artigas, M S, Shete, S, Brenner, H, Chanock, S, Brennan, P, McKay, J D & Amos, C I 2020, ' Protein-altering germline mutations implicate novel genes related to lung cancer development ', Nature Communications, vol. 11, no. 1, 2220 . https://doi.org/10.1038/s41467-020-15905-6, NATURE COMMUNICATIONS, Nature Communications, 11, Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020), Nat. Commun. 11:2220 (2020), Nature Communications, 11, 1, Nature Communications, 11(1):2220. Nature Publishing Group
- Accession number :
- edsair.doi.dedup.....80c1ad9b0468ae710d33bb5a662fc60b
- Full Text :
- https://doi.org/10.1038/s41467-020-15905-6