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Endoscopic treatment of colorectal neoplasms: a simple and safe procedure to lower the incidence of colorectal cancers
- Source :
- Digestive diseases and sciences. 53(5)
- Publication Year :
- 2005
-
Abstract
- Aim For many physicians who ordinarily treat patients with colonic diseases, colonoscopy is considered a prime study interest. Developments in colonoscopic equipment and methods have led to larger numbers of endoscopic diagnoses and treatments for colorectal neoplasms. The purpose of this investigation is to evaluate the efficacy and outcomes of endoscopic treatment for colorectal neoplastic lesions and the development of colorectal cancers after colonoscopic therapy. Materials and methods From September 1999 to May 2005, 19,815 consecutive colonoscopic examinations in 16,318 patients were gathered, totaling 9,534 endoscopic treatments for colorectal neoplasms. Macroscopic characteristics of the neoplasms were classified into protruded (N = 7,455), sessile (N = 1,569), lateral spreading tumor (N = 201), depressed lesions (N = 21), and flat lesions (N = 288). Snare polypectomy was conducted in 7,536 lesions, hot forceps removal in 1,545 lesions, and endoscopic mucosal resection in 353 lesions. Results Histological diagnoses were 8,333 neoplastic lesions (8,246 adenomas with low/high-grade dysplasia and 87 invasive adenocarcinomas) and 1,201 non-neoplastic lesions (1,186 hyperplastic and 15 inflammatory polyps). For the adenocarcinoma group, all had received further operations, while 73 surgical specimens discovered no residual tumors. Four perforations and 146 bleedings were found following endoscopic treatment. No procedure-related mortality was found and no recurrent malignancy was found after 6-71 months follow-up. Conclusion To lower the incidence and mortality of advanced colorectal cancer, endoscopic treatment for colorectal neoplasms is a simple and safe procedure.
- Subjects :
- Adult
Male
medicine.medical_specialty
Adolescent
Physiology
Colorectal cancer
medicine.medical_treatment
Colonoscopy
Colonic Polyps
Endoscopic mucosal resection
Malignancy
Gastroenterology
Internal medicine
medicine
Humans
Neoplasm Invasiveness
Aged
Aged, 80 and over
medicine.diagnostic_test
business.industry
Cancer
Middle Aged
medicine.disease
Polypectomy
Treatment Outcome
Dysplasia
Adenocarcinoma
Female
Neoplasm Recurrence, Local
business
Colorectal Neoplasms
Subjects
Details
- ISSN :
- 01632116
- Volume :
- 53
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Digestive diseases and sciences
- Accession number :
- edsair.doi.dedup.....804698d3369a3b2b9808606f166d1b3c