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Prognosis and longitudinal changes of physical activity in idiopathic pulmonary fibrosis
- Source :
- BMC Pulmonary Medicine, Vol 17, Iss 1, Pp 1-8 (2017), Publons, BMC Pulmonary Medicine
- Publication Year :
- 2017
- Publisher :
- BMC, 2017.
-
Abstract
- Background: Physical activity (PA) is associated with disease severity in idiopathic pulmonary fibrosis (IPF), but longitudinal studies evaluating its prognostic value and changes over time are lacking. Methods: We measured PA (steps per day, SPD) in a cohort of 46 IPF-patients (mean age, 67 years; mean FVC, 76.1%pred.) by accelerometry at baseline, recorded survival status during 3 years follow-up and repeated measurements in survivors. We compared the prognostic value of PA to established mortality predictors including lung function (FVC, DLCO) and 6-min walking-distance (6MWD). Results: During follow-up (median 34 months) 20 patients (43%) died. SPD and FVC best identified non-survivors (AUROC-curve 0.79, p
- Subjects :
- Male
Vital Capacity
Walking
Idiopathic pulmonary fibrosis
610 Medical sciences Medicine
0302 clinical medicine
DLCO
Accelerometry
030212 general & internal medicine
Carbon Monoxide
Exercise Tolerance
Longitudinal studies
Confounding
Middle Aged
respiratory system
Prognosis
Survival Rate
Triaxial accelerometer
Area Under Curve
Cohort
Disease Progression
Cardiology
Female
Research Article
Pulmonary and Respiratory Medicine
medicine.medical_specialty
Physical activity
Walk Test
Physical exercise
Functional status (activity levels)
03 medical and health sciences
FEV1/FVC ratio
Disease severity
Predictive Value of Tests
Internal medicine
medicine
Humans
Mortality
Aged
lcsh:RC705-779
business.industry
lcsh:Diseases of the respiratory system
medicine.disease
ROC Curve
030228 respiratory system
Physical therapy
Pulmonary Diffusing Capacity
business
Subjects
Details
- Language :
- English
- ISSN :
- 14712466
- Volume :
- 17
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- BMC Pulmonary Medicine
- Accession number :
- edsair.doi.dedup.....802f444b2d27719536bf9147eff2cf72