Weight as Predictors of Clinical Progression and Treatment Failure

Authors :: Azar, Kariminia
Nicolas, Durier
Gonzague, Jourdain
Suneeta, Saghayam
Chau V, Do
Lam Van, Nguyen
Rawiwan, Hansudewechakul
Pagakrong, Lumbiganon
Kulkanya, Chokephaibulkit
Khanh Huu, Truong
Virat, Sirisanthana
Vibol, Ung
Saphonn, Vonthanak
Jintanat, Ananworanich
Nik Khairulddin, Nik Yusoff
Nia, Kurniati
Kamarul, Azahar Razali
Moy Siew, Fong
Revathy, Nallusamy
Dewi Kumara, Wati
M G, Law
Source :: JAIDS Journal of Acquired Immune Deficiency Syndromes. 67:71-76
Publication Year :: 2014
Publisher :: Ovid Technologies (Wolters Kluwer Health), 2014.
Abstract: Objective: To evaluate the value of time-updated weight and height in predicting clinical progression, and immunological and virological failure in children receiving combination antiretroviral therapy (cART). Methods: We used Cox regression to analyze data of a cohort of Asian children. Results: A total of 2608 children were included; median age at cART was 5.7 years. Time-updated weight for age z score, 23 was associated with mortality (P < 0.001) independent of CD4% and < -2 was associated with immunological failure (P

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