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Author Correction: N-Alkylation of functionalized amines with alcohols using a copper–gold mixed photocatalytic system

Authors :
Lyu-Ming Wang
Susumu Saito
Hiroshi Naka
Kellie J. Jenkinson
Andrew E. H. Wheatley
Yuna Morioka
Source :
Scientific Reports, Scientific Reports, Vol 8, Iss 1, Pp 1-3 (2018)
Publication Year :
2018
Publisher :
Springer Science and Business Media LLC, 2018.

Abstract

Direct functionalization of amino groups in complex organic molecules is one of the most important key technologies in modern organic synthesis, especially in the synthesis of bio-active chemicals and pharmaceuticals. Whereas numerous chemical reactions of amines have been developed to date, a selective, practical method for functionalizing complex amines is still highly demanded. Here we report the first late-stage N-alkylation of pharmaceutically relevant amines with alcohols at ambient temperature. This reaction was achieved by devising a mixed heterogeneous photocatalyst in situ prepared from Cu/TiO

Details

ISSN :
20452322
Volume :
8
Database :
OpenAIRE
Journal :
Scientific Reports
Accession number :
edsair.doi.dedup.....7fd21d7b9d392652cbc87cf814ab3756