Back to Search Start Over

Analyzing the Impact of the Substituent on the Quinazolinone Schiff Base and the Interaction of the Fe (III) and Cr (III) with Different Quinazolinone Schiff Base for Antioxidant and Anti-inflammatory Activity

Authors :
Pore, Avinash
Gaikwad, Gautam
Hegade, Sujit
Jadhav, Yuvraj
Mane, Ravindra
Kumbhar, Rajendra
Source :
Analytical Chemistry Letters. 13:39-59
Publication Year :
2023
Publisher :
Informa UK Limited, 2023.

Abstract

Schiff base and their Fe (III), Cr (III) complexes stood vetted for Antioxidant, Anti-inflammatory activities and docking study. Mixed ligand complexes had strong antioxidant and anti-inflammatory properties. Docking study of mixed ligand complexes reveals substantial binding affinity for COX2 and STAT3 receptors. The experimental and computational anti-inflammatory and antioxidant activity results are more consistent.

Subjects

Subjects :
Earth-Surface Processes

Details

ISSN :
22307532 and 22297928
Volume :
13
Database :
OpenAIRE
Journal :
Analytical Chemistry Letters
Accession number :
edsair.doi.dedup.....7f3a07d79c77e7402091e6f12b1cf80c