Back to Search Start Over

Figure S1 from Preclinical Comparison of the Blood–brain barrier Permeability of Osimertinib with Other EGFR TKIs

Authors :
Darren A.E. Cross
Zack Cheng
Lars Farde
Paul D. Smith
James W.T. Yates
Richard A. Ward
M. Raymond V. Finlay
Natasha A. Karp
Albert D. Windhorst
Mohammad Mahdi Moein
Ana Vazquez-Romero
Evgeny Revunov
Jonas Malmquist
Mikhail Kondrashov
Ryosuke Arakawa
Akihiro Takano
Aaron Smith
Joanne Wilson
Annika Janefeldt
Lin Zhang
James Atkinson
Peter Barton
Gareth Maglennon
Don X. Nguyen
Minghui Zhao
Sally J. Adua
Katarina Varnäs
Richard Goodwin
Magnus Schou
Gail L. Wrigley
Yumei Yan
Nicole Strittmatter
Peter Johnström
Kan Chen
Nicola Colclough
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Supplementary Figure S1 - Structure and position of label for compounds assessed for BBB penetrance in non human primates (NHP). Majority of compounds were labelled with carbon-11 except afatinib which was labelled with fluorine-18. (*) Indicates position for carbon-11 label

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....7f25e8e82af5345d6a7e68e8c3a46ea5