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Mass spectrometry in high-throughput proteomics: ready for the big time

Authors :
John R. Yates
Ruedi Aebersold
Matthias Mann
John J.M. Bergeron
Tommy Nilsson
Amos Marc Bairoch
Source :
Nature Methods, Vol. 7, No 9 (2010) pp. 681-5
Publication Year :
2010
Publisher :
Springer Science and Business Media LLC, 2010.

Abstract

Mass spectrometry has evolved and matured to a level where it is able to assess the complexity of the human proteome. We discuss some of the expected challenges ahead and promising strategies for success.

Details

ISSN :
15487105 and 15487091
Volume :
7
Database :
OpenAIRE
Journal :
Nature Methods
Accession number :
edsair.doi.dedup.....7e9714e8aa9faf914e31c4e2ba061206
Full Text :
https://doi.org/10.1038/nmeth0910-681