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Graph analysis of EEG resting state functional networks in dyslexic readers
- Source :
- Clinical Neurophysiology, 127(9), 3165-3175. Elsevier, Clinical Neurophysiology, 127(9), 3165-3175. Elsevier Ireland Ltd, Gonzalez, G F, Van der Molen, M J W, Zaric, G, Bonte, M, Tijms, J, Blomert, L, Stam, C J & Van der Molen, M W 2016, ' Graph analysis of EEG resting state functional networks in dyslexic readers ', Clinical Neurophysiology, vol. 127, no. 9, pp. 3165-3175 . https://doi.org/10.1016/j.clinph.2016.06.023
- Publication Year :
- 2016
-
Abstract
- ObjectiveNeuroimaging research suggested a mixed pattern of functional connectivity abnormalities in developmental dyslexia. We examined differences in the topological properties of functional networks between 29 dyslexics and 15 typically reading controls in 3rd grade using graph analysis. Graph metrics characterize brain networks in terms of integration and segregation.MethodWe used EEG resting-state data and calculated weighted connectivity matrices for multiple frequency bands using the phase lag index (PLI). From the connectivity matrices we derived minimum spanning tree (MST) graphs representing the sub-networks with maximum connectivity. Statistical analyses were performed on graph-derived metrics as well as on the averaged PLI connectivity values.ResultsWe found group differences in the theta band for two graph metrics suggesting reduced network integration and communication between network nodes in dyslexics compared to controls.ConclusionCollectively, our findings point to a less efficient network configuration in dyslexics relative to the more proficient configuration in the control group.SignificanceGraph metrics relate to the intrinsic organization of functional brain networks. These metrics provide additional insights on the cognitive deficits underlying dyslexia and, thus, may advance our knowledge on reading development. Our findings add to the growing body literature suggesting compromised networks rather than specific dysfunctional brain regions in dyslexia.
- Subjects :
- Power graph analysis
Male
DISRUPTION
Computer science
CHILDREN
Network
Electroencephalography
Minimum spanning tree
Brain mapping
Dyslexia
Functional connectivity
0302 clinical medicine
FMRI CONNECTIVITY
Child
COMPLEX BRAIN NETWORKS
Brain Mapping
NEURAL SYSTEMS
medicine.diagnostic_test
05 social sciences
Brain
Cognition
Sensory Systems
Neurology
Female
THEORETICAL ANALYSIS
Rest
Clinical Neurology
ORGANIZATION
050105 experimental psychology
03 medical and health sciences
Physiology (medical)
medicine
OSCILLATIONS
Humans
0501 psychology and cognitive sciences
Electroencephalography (EEG)
Communication
Resting state fMRI
business.industry
Graph theory
Pattern recognition
medicine.disease
Reading
TASK
Neurology (clinical)
Artificial intelligence
Nerve Net
business
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- ISSN :
- 13882457
- Database :
- OpenAIRE
- Journal :
- Clinical Neurophysiology, 127(9), 3165-3175. Elsevier, Clinical Neurophysiology, 127(9), 3165-3175. Elsevier Ireland Ltd, Gonzalez, G F, Van der Molen, M J W, Zaric, G, Bonte, M, Tijms, J, Blomert, L, Stam, C J & Van der Molen, M W 2016, ' Graph analysis of EEG resting state functional networks in dyslexic readers ', Clinical Neurophysiology, vol. 127, no. 9, pp. 3165-3175 . https://doi.org/10.1016/j.clinph.2016.06.023
- Accession number :
- edsair.doi.dedup.....7e62e6a04696b906ad928f4c6424e693