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Global Endometrial Ablation for Menorrhagia in Women With Bleeding Disorders
- Source :
- Obstetrics & Gynecology. 109:1381-1387
- Publication Year :
- 2007
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2007.
-
Abstract
- Objective To evaluate the efficacy of global endometrial ablation in women with bleeding disorders who presented with menorrhagia. Methods A records-linkage system was used to construct a retrospective cohort of 41 women with bleeding disorders (coagulopathy) and a reference group of 111 randomly selected women without bleeding disorders from a pool of 943 women who underwent global endometrial ablation (with thermal balloon ablation technology or bipolar radiofrequency ablation technology) for menorrhagia at Mayo Clinic (Rochester, Minnesota) from January 1995 through December 2005. Demographic data, type of global endometrial ablation therapy and reablation, and hysterectomy data were extracted from the database. Results There was no significant difference in baseline age, parity, body mass index, uterine size, type of global endometrial ablation therapy, or duration of follow-up between the groups. Two women (5%) in the coagulopathy group had hysterectomy or reablation, compared with 8 (7%) in the reference group (Fisher exact test, P=.728). A Kaplan-Meier plot showed no difference in the time to treatment failure between the groups (log-rank test, P=.534). Procedural-related complications were generally minor and infrequent (9 of 152 [6%]). Complications were equally distributed in the coagulopathy (4 of 41) and reference groups (6 of 111) (Fisher exact test, P=.267). Conclusion Global endometrial ablation is an effective treatment choice for women with coagulopathy presenting with menorrhagia.
- Subjects :
- Adult
Reoperation
medicine.medical_specialty
medicine.medical_treatment
Kaplan-Meier Estimate
Hysterectomy
law.invention
Cohort Studies
Endometrium
symbols.namesake
Randomized controlled trial
Recurrence
law
Coagulopathy
Humans
Medicine
Menorrhagia
Fisher's exact test
Retrospective Studies
Laser Coagulation
business.industry
Obstetrics and Gynecology
Retrospective cohort study
Blood Coagulation Disorders
Middle Aged
Ablation
medicine.disease
Surgery
Treatment Outcome
Catheter Ablation
Endometrial ablation
symbols
Female
business
Cohort study
Subjects
Details
- ISSN :
- 00297844
- Volume :
- 109
- Database :
- OpenAIRE
- Journal :
- Obstetrics & Gynecology
- Accession number :
- edsair.doi.dedup.....7e5dfda3c8f8d0009f39c50fb106eeeb