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2-Hydroxypropyl-β-cyclodextrin encapsulates dimethyl disulfide producing a controlled release formulation
- Source :
- Science of The Total Environment. 773:145293
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Dimethyl disulfide (DMDS), a soil fumigant, is an effective, broad-spectrum compound that often replaces bromomethane (MB) in the prevention and treatment of soil-borne diseases. However, the disadvantages of DMDS include toxicity, volatility, pungent odor, risk of human exposure, and environmental pollution. Cyclodextrin (CD) has been widely used as a carrier of chemicals in many industries due to its functional advantages and safety. In this study, a DMDS-controlled release formulation was developed by encapsulating DMDS in the cavity of 2-hydroxypropyl-β-cyclodextrin (HP-β-CD). This formulation reduced DMDS usage and production costs. Orthogonal experimental design, Fourier transform infrared (FT-IR), Scanning electron microscopy (SEM), Thermal gravity analysis (TGA) characterization, efficacy comparison, safety, and other aspects of the evaluation showed that under the best preparation conditions, the encapsulation rate was 81.49%. The efficacy of DMDS@HP-β-CD was similar to unformulated DMDS. The efficacy duration of the formulation was about two times longer than DMDS, and it was safer to use. This study reveals a cyclodextrin-DMDS formulation with reduced toxicity, longer duration, environmental safety and sustainability.
- Subjects :
- chemistry.chemical_classification
Environmental Engineering
Bromomethane
010504 meteorology & atmospheric sciences
Cyclodextrin
Chemistry
Environmental pollution
010501 environmental sciences
01 natural sciences
Pollution
Controlled release
2-Hydroxypropyl-beta-cyclodextrin
chemistry.chemical_compound
2 hydroxypropyl β cyclodextrin
Odor
Reduced toxicity
Delayed-Action Preparations
Spectroscopy, Fourier Transform Infrared
Humans
Environmental Chemistry
Organic chemistry
Dimethyl disulfide
Disulfides
Waste Management and Disposal
0105 earth and related environmental sciences
Subjects
Details
- ISSN :
- 00489697
- Volume :
- 773
- Database :
- OpenAIRE
- Journal :
- Science of The Total Environment
- Accession number :
- edsair.doi.dedup.....7e4dab331135a78a1238f05dc1d59767