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Cutaneous and neurologic disease associated with HTLV-I infection
- Source :
- Journal of the American Academy of Dermatology. 36(5 Pt 2)
- Publication Year :
- 1997
-
Abstract
- Human T-lymphotropic virus type I (HTLV-I) is the etiologic agent of HTLV-I associated myelopathy (HAM)/tropical spastic paresis (TSP), and adult T-cell leukemia/lymphoma (ATLL). ATLL has been associated with HTLV-I in the southeastern United States. However, to our knowledge, no case reports of HAM/TSP in association with ATLL occurring in the United States have been described. We describe a 40-year-old black woman with a 10-year history of recalcitrant psoriasiform eruption and erythrodermic flares. Medical history is additionally significant for a 2-year history of HTLV-I-associated myelopathy and lower extremity spastic paresis. Polymerase chain reaction with Southern blot analysis was used to detect HTLV-I proviral genome from frozen skin biopsy specimens and peripheral blood mononuclear cells.
- Subjects :
- Adult
Pathology
medicine.medical_specialty
viruses
Dermatology
Peripheral blood mononuclear cell
Polymerase Chain Reaction
Skin Diseases
Virus
Immunophenotyping
Myelopathy
immune system diseases
hemic and lymphatic diseases
Medicine
Humans
Leukemia-Lymphoma, Adult T-Cell
Medical history
Skin
Human T-lymphotropic virus 1
medicine.diagnostic_test
business.industry
virus diseases
medicine.disease
Paraparesis, Tropical Spastic
Lymphoma
Leukemia
Skin biopsy
Female
Viral disease
business
Subjects
Details
- ISSN :
- 01909622
- Volume :
- 36
- Issue :
- 5 Pt 2
- Database :
- OpenAIRE
- Journal :
- Journal of the American Academy of Dermatology
- Accession number :
- edsair.doi.dedup.....7e2f7457626ed860e10878c66158900b