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Soluble LAG-3 and Toll-interacting protein: Novel upstream neuro-inflammatory markers in Parkinson's disease
- Source :
- Parkinsonismrelated disorders. 91
- Publication Year :
- 2021
-
Abstract
- Introduction There is some evidence regarding the role of LAG-3, TLR mediated neuroinflammation in PD. Methods sLAG-3, TOLLIP, NLRP3 levels were measured in PD and healthy controls. Results These markers were significantly higher in PD and were associated with progression. Conclusion sLAG3 and TOLLIP are involved in the NLRP3 mediated inflammatory activation in PD.
- Subjects :
- Male
Parkinson's disease
integumentary system
business.industry
TOLLIP
Intracellular Signaling Peptides and Proteins
Parkinson Disease
medicine.disease
Lymphocyte Activation Gene 3 Protein
Neuro inflammation
Neurology
Antigens, CD
Case-Control Studies
Immunology
NLR Family, Pyrin Domain-Containing 3 Protein
Neuroinflammatory Diseases
medicine
Humans
Toll-Interacting Protein
Female
Neurology (clinical)
Geriatrics and Gerontology
business
Neuroinflammation
Biomarkers
Subjects
Details
- ISSN :
- 18735126
- Volume :
- 91
- Database :
- OpenAIRE
- Journal :
- Parkinsonismrelated disorders
- Accession number :
- edsair.doi.dedup.....7dfd07ef6dd4af08862ae682d9e7c21b