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Progress in protecting vestibular hair cells
- Source :
- Arch Toxicol, Archives of Toxicology
- Publication Year :
- 2021
-
Abstract
- Vestibular hair cells are mechanosensory receptors that are capable of detecting changes in head position and thereby allow animals to maintain their posture and coordinate their movement. Vestibular hair cells are susceptible to ototoxic drugs, aging, and genetic factors that can lead to permanent vestibular dysfunction. Vestibular dysfunction mainly results from the injury of hair cells, which are located in the vestibular sensory epithelium. This review summarizes the mechanisms of different factors causing vestibular hair cell damage and therapeutic strategies to protect vestibular hair cells.
- Subjects :
- 0301 basic medicine
Aging
Ototoxic drugs
Health, Toxicology and Mutagenesis
Pharmacology toxicology
Review Article
Hair cells
Toxicology
Epithelium
03 medical and health sciences
Hair Cells, Vestibular
0302 clinical medicine
otorhinolaryngologic diseases
Medicine
Animals
Humans
Vestibular dysfunction
Vestibular Hair Cell
Protection
integumentary system
business.industry
Correction
General Medicine
Ototoxicity
030104 developmental biology
Vestibular Diseases
Vestibular sensory epithelium
Head position
sense organs
business
Neuroscience
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 14320738
- Volume :
- 95
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Archives of toxicology
- Accession number :
- edsair.doi.dedup.....7ddb48eb64db306246713e432fd85aaf