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Progress in protecting vestibular hair cells

Authors :
Luoying Jiang
Yingzi He
Zhiwei Zheng
Source :
Arch Toxicol, Archives of Toxicology
Publication Year :
2021

Abstract

Vestibular hair cells are mechanosensory receptors that are capable of detecting changes in head position and thereby allow animals to maintain their posture and coordinate their movement. Vestibular hair cells are susceptible to ototoxic drugs, aging, and genetic factors that can lead to permanent vestibular dysfunction. Vestibular dysfunction mainly results from the injury of hair cells, which are located in the vestibular sensory epithelium. This review summarizes the mechanisms of different factors causing vestibular hair cell damage and therapeutic strategies to protect vestibular hair cells.

Details

ISSN :
14320738
Volume :
95
Issue :
8
Database :
OpenAIRE
Journal :
Archives of toxicology
Accession number :
edsair.doi.dedup.....7ddb48eb64db306246713e432fd85aaf