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Smooth Muscle and Other Cell Sources for Human Blood Vessel Engineering
- Publication Year :
- 2011
- Publisher :
- S. Karger AG, 2011.
-
Abstract
- Despite substantial progress in the field of vascular tissue engineering over the past decades, transition to human models has been rather challenging. The limited replicative life spans of human adult vascular cells, and their slow rate of collagenous matrix production in vitro, have posed important hurdles in the development of mechanically robust and biologically functional engineered grafts. With the more recent advances in the field of stem cells, investigators now have access to a plethora of new cell source alternatives for vascular engineering. In this paper, we review various alternative cell sources made available more recently for blood vessel engineering and also present some recent data on the derivation of smooth muscle cells from human induced pluripotent stem cells.
- Subjects :
- Paper
Histology
Tissue Engineering
Induced Pluripotent Stem Cells
Myocytes, Smooth Muscle
Anatomy
Biology
Cell biology
Blood Vessel Prosthesis
Endothelial stem cell
medicine.anatomical_structure
Tissue engineering
Blood vessel prosthesis
medicine
Myocyte
Animals
Humans
Stem cell
Induced pluripotent stem cell
Blood vessel
Stem cell transplantation for articular cartilage repair
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....7dc845edb30df89a89e9cdf5a67bc7b8