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Stochastic dynamics and survival analysis of a cell population model with random perturbations

Authors :
Cristina Anton
Alan Yong
Source :
Mathematical Biosciences & Engineering. 15:1077-1098
Publication Year :
2018
Publisher :
American Institute of Mathematical Sciences (AIMS), 2018.

Abstract

We consider a model based on the logistic equation and linear kinetics to study the effect of toxicants with various initial concentrations on a cell population. To account for parameter uncertainties, in our model the coefficients of the linear and the quadratic terms of the logistic equation are affected by noise. We show that the stochastic model has a unique positive solution and we find conditions for extinction and persistence of the cell population. In case of persistence we find the stationary distribution. The analytical results are confirmed by Monte Carlo simulations.

Details

ISSN :
15471063
Volume :
15
Database :
OpenAIRE
Journal :
Mathematical Biosciences & Engineering
Accession number :
edsair.doi.dedup.....7d4d7eb62b64baf93b8f6fba959b96dd