ACEI-Inhibitory Peptides Naturally Generated in Meat and Meat Products and Their Health Relevance

Meat and meat products have been described as a very good source of angiotensin I converting enzyme (ACEI)-inhibitory peptides. The generation of bioactive peptides can occur through the action of endogenous muscular enzymes during processing, gastrointestinal digestion, or by using commercial enzymes in laboratory or industry under controlled conditions. Studies of bioavailability are necessary in order to prove the positive health effect of bioactive peptides in the body as they should resist gastrointestinal digestion, cross the intestinal barrier, and reach blood stream and target organs. However, in order to better understand their effect, interactions, and bioavailability, it is necessary to consider food matrix interactions and continue the development of quantitative methodologies in order to obtain more data that will enable advances in the field of bioactive peptides and the determination of their influence on health.
This research was funded by grant AGL2017-89381-R and FEDER funds from the Spanish Ministry of Science, Innovation, and Universities. Ramón y Cajal postdoctoral contract to L.M. is also acknowledged.