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Vitamin D3 and its receptor in selected obstetrical complications
- Source :
- Ginekologia Polska.
- Publication Year :
- 2021
- Publisher :
- VM Media SP. zo.o VM Group SK, 2021.
-
Abstract
- Vitamin D3 (VD3) and its steroidal nuclear receptor are necessary for proper development of a pregnancy. They play a key role in implantation, modulate the mother's immune response to the developing fetus, influence the final development of a placenta, and regulate blood pressure and glucose tolerance. VD3 deficiency can lead to the occurrence of obstetric complications such as recurrent miscarriages, preeclampsia, intrauterine growth restriction, gestational diabetes and preterm labor. VD3 deficiency is a common phenomenon across the globe; because of the higher demand placed on their bodies, pregnant women are more likely to develop VD3 deficiency. During pregnancy, VD3 supplementation is a safe method of treatment without risk of side effects or intoxication. To obtain the greatest efficacy, VD3 supplementation should start at the pregnancy planning stage, under control of the VD3 serum concentration, which should exceed 30 ng/mL (75 nmol/L); this is to start the positive effect of the optimal VD3 concentration from the beginning of a pregnancy.
- Subjects :
- Vitamin
Pregnancy
medicine.medical_specialty
Fetus
business.industry
Obstetrics
Obstetrics and Gynecology
Intrauterine growth restriction
medicine.disease
Preeclampsia
Gestational diabetes
chemistry.chemical_compound
medicine.anatomical_structure
chemistry
Placenta
Vitamin D and neurology
Medicine
business
Subjects
Details
- ISSN :
- 25436767 and 00170011
- Database :
- OpenAIRE
- Journal :
- Ginekologia Polska
- Accession number :
- edsair.doi.dedup.....7d054e3e726d11a8ac20c44a61778fc4