Stable Reversion of Conventional Human Pluripotent Stem Cells to a Mouse ESC-like Naïve Ground State Erases Somatic Donor Epigenetic Memory and Significantly Improves Their Hemato-Vascular Differentiation Potency

Authors :: Yang W. Zhang
Tea Soon Park
Michael Considine
Jasmin Agarwal
Stephen B. Baylin
Karan Verma
Alan D. Friedman
Sarshan R. Pather
C. Conover Talbot
Elias T. Zambidis
Hong Guo
Diana Steppan
Leslie Cope
Ludovic Zimmerlin
Jeffrey S. Huo
Source :: Biology of Blood and Marrow Transplantation. 22:S426
Publication Year :: 2016
Publisher :: Elsevier BV, 2016.

Subjects :: Genetics
Transplantation
Somatic cell
Reversion
Potency
Hematology
Epigenetics
Biology
Induced pluripotent stem cell
Cell biology

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