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A Case of Neurotrophic Keratopathy Associated with Nasopharyngeal Carcinoma
- Source :
- Case Reports in Ophthalmology, Vol 9, Iss 1, Pp 114-118 (2018), Case Reports in Ophthalmology
- Publication Year :
- 2018
- Publisher :
- S. Karger AG, 2018.
-
Abstract
- Purpose: To report a case of neurotrophic keratopathy associated with nasopharyngeal carcinoma. Case Report: A 59-year-old man who had been diagnosed with a nasopharyngeal carcinoma was referred to the authors because of visual disturbance and pain in his right eye. Slit-lamp examination revealed a corneal epithelial defect and corneal stromal edema surrounding the epithelial defect area in his right eye. Magnetic resonance imaging showed a mass in his cavernous sinus, which was identified as nasopharyngeal carcinoma (NPC). We diagnosed neurotrophic keratopathy associated with NPC and initiated treatment with preservative-free artificial tears, antibiotic eye drops, fibronectin, a therapeutic contact lens, and amniotic membrane transplantation. However, the persistent corneal epithelial defect was unresponsive to these treatments. Conclusion: Neurotrophic keratopathy secondary to NPC is thought to be rare. We presented a case of neurotrophic keratopathy associated with cavernous sinus metastasis of an NPC. The development of new and more effective treatments for this refractory disease is anticipated.
- Subjects :
- Pathology
medicine.medical_specialty
genetic structures
Neurotrophic keratopathy
medicine.medical_treatment
Case Report
Metastasis
03 medical and health sciences
0302 clinical medicine
lcsh:Ophthalmology
Nasopharyngeal carcinoma
otorhinolaryngologic diseases
Medicine
Cavernous sinus
Corneal stromal edema
medicine.diagnostic_test
business.industry
Magnetic resonance imaging
medicine.disease
eye diseases
Transplantation
Ophthalmology
Artificial tears
lcsh:RE1-994
030221 ophthalmology & optometry
sense organs
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 16632699
- Volume :
- 9
- Database :
- OpenAIRE
- Journal :
- Case Reports in Ophthalmology
- Accession number :
- edsair.doi.dedup.....7c4768d83117cde79a80be0e5e0de941