Evidence-based therapy with Krka’s statins in patients in primary and secondary prevention of cardiovascular disease

Dokazano je da statini smanjuju kardiovaskularni pobol i smrtnost u primarnoj i sekundarnoj prevenciji kardiovaskularnih bolesti. No liječenje statinima još uvijek nije optimalno jer većina pacijenata ne postiže najveće moguće pozitivne učinke ovakve preventivne strategije. Krka ima širok raspon statina koji su iscrpno testirani. Studije donose jasne i opsežne dokaze o dobrobiti primjene atorvastatina (Atoris®) irosuvastatina (Roswera®) u primarnoj i sekundarnoj prevenciji, uključujući uspješno liječenje ukupnoga lipidnog profila, postizanje ciljne razine lipida, prevencije ozbiljnih ishemijskih ishoda u pacijenata s akutnim koronarnim sindromom, preventivne pleiotropne učinke i dobar sigurnosni profil. Kliničke studije na Krkinim statinima važan su doprinos boljem liječenju hiperlipidemije u različinim skupinama pacijenata.
Statins have been proven to reduce cardiovascular morbidity and mortality in primary and secondary prevention of cardiovascular disease. However, statin treatment is still not optimal, with the majority of patients not achieving the maximum benefits of this preventive strategy. Krka offers a wide range of statins that have been extensively studied. The studies have provided clear and conclusive evidence about the benefits of atorvastatin (Atoris®) and rosuvastatin (Roswera®) in primary and secondary prevention patients, including effective management of the total lipid profile, achievement of target lipid levels, prevention of severe ischemic outcomes in patients with acute coronary syndrome, protective pleiotropic effects and a good safety profile. Clinical studies with Krka’s statins represent an important contribution to a better management of hyperlipidemia in different groups of patients