On the problem of local antibiotic therapy in children with ocular surface diseases

The efficacy and safety of topical Azithromycin ophthalmic solution 1.5 % has been evaluated in treatment of bacterial conjunctivitis and post-traumatic keratitis in children, and the possibility of its use for prevention of infectious complications after ocular surface trauma. Topical Azithromycin ophthalmic solution 1.5 % was used in 32 children: with bacterial conjunctivitis (21), corneal foreign body (5), traumatic corneal erosion (3), post-traumatic keratitis (3). Topical Azithromycin ophthalmic solution 1.5% was shown to have a significant antibacterial activity and a convenient dosing schedule. No side effects, including eye irritation, have been noted. Conclusion: topical Azithromycin ophthalmic solution 1.5 % could be considered as the medication of choice in treatment of bacterial conjunctivitis and post-traumatic keratitis in children. It also could be used in the complex prevention of infections complications in eye surface traumatic lesions.