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Acquired Gaucher's cells in Hodgkin's disease
- Source :
- The American journal of medicine. 73(2)
- Publication Year :
- 1982
-
Abstract
- A patient with Hodgkin's disease associated with low glucocerebrosidase levels in the peripheral leukocytes, and Gaucher's cells in the bone marrow and lymph nodes, is described. After MOPP therapy, complete remission of Hodgkin's disease was accompanied by normalization of the glucocerebrosidase level and disappearance of Gaucher's cells. This observation appears unique when compared with the four cases of combined Hodgkin's and Gaucher's disease reported in earlier literature in which Gaucher's disease remained unchanged after chemotherapy. We conclude that our patient had Hodgkin's disease and acquired Gaucher's cells with diminished glucocerebrosidase levels, rather than a combination of Hodgkin's disease and Gaucher's disease.
- Subjects :
- Adult
Male
congenital, hereditary, and neonatal diseases and abnormalities
Pathology
medicine.medical_specialty
medicine.medical_treatment
Disease
immune system diseases
Bone Marrow
hemic and lymphatic diseases
medicine
Leukocytes
Humans
Aged
Hodgkin s
Chemotherapy
Gaucher Disease
business.industry
Complete remission
nutritional and metabolic diseases
General Medicine
Middle Aged
Hodgkin Disease
nervous system diseases
medicine.anatomical_structure
Glucosylceramidase
Female
Bone marrow
Lymph
Lymph Nodes
business
Glucocerebrosidase
Glucosidases
Subjects
Details
- ISSN :
- 00029343
- Volume :
- 73
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- The American journal of medicine
- Accession number :
- edsair.doi.dedup.....7bd23e4e9fea45b4c6ca97af1230c5d1