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Supplementary Table 6 from Expression Levels of Therapeutic Targets as Indicators of Sensitivity to Targeted Therapeutics

Authors :
Alistair R.R. Forrest
Timo Lassmann
Louise N. Winteringham
Riti Roy
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Supplementary Table 6a: Spearman correlation values between drug sensitivity and target expression for 86 drugs common between GDSC and CTRP. Supplementary Table 6b: Correlation matrix comparing gene expression values. There are 558 cell lines and 15,934 genes common between both the datasets. Calculated 558x 558 - Correlation matrix comparing gene expression values for 15,934 genes in one cell line from GDSC compared to 15,934 genes in CTRP. Correlation method used was Spearman. Supplementary Table 6c: Spearman correlation values comparing Area under the curve (AUC) values across common cell lines in the GDSC and CTRP datasets for the 86 drugs common between them. Supplementary Table 6d: List of the cell lines where a better gene expression correlation was observed with a different cell line.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....7b94f6841494ae3ff91861d5cd3ba67f
Full Text :
https://doi.org/10.1158/1535-7163.22510665