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Bats host major mammalian paramyxoviruses
- Source :
- Nature Communications, Nature Communications, Nature Publishing Group, 2012, 3, pp.796. ⟨10.1038/ncomms1796⟩, Nature Communications; Vol 3, Nature Communications, 2012, 3, pp.796. ⟨10.1038/ncomms1796⟩
- Publication Year :
- 2012
- Publisher :
- HAL CCSD, 2012.
-
Abstract
- The large virus family Paramyxoviridae includes some of the most significant human and livestock viruses, such as measles-, distemper-, mumps-, parainfluenza-, Newcastle disease-, respiratory syncytial virus and metapneumoviruses. Here we identify an estimated 66 new paramyxoviruses in a worldwide sample of 119 bat and rodent species (9,278 individuals). Major discoveries include evidence of an origin of Hendra- and Nipah virus in Africa, identification of a bat virus conspecific with the human mumps virus, detection of close relatives of respiratory syncytial virus, mouse pneumonia- and canine distemper virus in bats, as well as direct evidence of Sendai virus in rodents. Phylogenetic reconstruction of host associations suggests a predominance of host switches from bats to other mammals and birds. Hypothesis tests in a maximum likelihood framework permit the phylogenetic placement of bats as tentative hosts at ancestral nodes to both the major Paramyxoviridae subfamilies (Paramyxovirinae and Pneumovirinae). Future attempts to predict the emergence of novel paramyxoviruses in humans and livestock will have to rely fundamentally on these data.<br />The large virus family, Paramyxoviridae, includes several human and livestock viruses. This study, testing 119 bat and rodent species distributed globally, identifies novel putative paramyxovirus species, providing data with potential uses in predictions of the emergence of novel paramyxoviruses in humans and livestock.
- Subjects :
- animal structures
Paramyxoviridae
viruses
Molecular Sequence Data
General Physics and Astronomy
Mumps virus
medicine.disease_cause
Article
General Biochemistry, Genetics and Molecular Biology
Mice
03 medical and health sciences
Pneumovirinae
Dogs
Chiroptera
Veterinary virology
medicine
Animals
Humans
Phylogeny
Disease Reservoirs
030304 developmental biology
Mammals
0303 health sciences
Paramyxoviridae Infections
Multidisciplinary
Ebola virus
biology
030306 microbiology
Canine distemper
General Chemistry
biology.organism_classification
medicine.disease
Virology
Sendai virus
3. Good health
[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology
Henipavirus
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Database :
- OpenAIRE
- Journal :
- Nature Communications, Nature Communications, Nature Publishing Group, 2012, 3, pp.796. ⟨10.1038/ncomms1796⟩, Nature Communications; Vol 3, Nature Communications, 2012, 3, pp.796. ⟨10.1038/ncomms1796⟩
- Accession number :
- edsair.doi.dedup.....7b8eeda7c2b6391d08b83e22653f7c62