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Cryptococcus gattiiInfections in Multiple States Outside the US Pacific Northwest
- Source :
- Emerging Infectious Diseases, Emerging Infectious Diseases, Vol 19, Iss 10, Pp 1621-1627 (2013)
- Publication Year :
- 2013
- Publisher :
- Centers for Disease Control and Prevention (CDC), 2013.
-
Abstract
- Clonal VGII subtypes (outbreak strains) of Cryptococcus gattii have caused an outbreak in the US Pacific Northwest since 2004. Outbreak-associated infections occur equally in male and female patients (median age 56 years) and usually cause pulmonary disease in persons with underlying medical conditions. Since 2009, a total of 25 C. gattii infections, 23 (92%) caused by non–outbreak strain C. gattii, have been reported from 8 non–Pacific Northwest states. Sixteen (64%) patients were previously healthy, and 21 (84%) were male; median age was 43 years (range 15–83 years). Ten patients who provided information reported no past-year travel to areas where C. gattii is known to be endemic. Nineteen (76%) patients had central nervous system infections; 6 (24%) died. C. gattii infection in persons without exposure to known disease-endemic areas suggests possible endemicity in the United States outside the outbreak-affected region; these infections appear to differ in clinical and demographic characteristics from outbreak-associated C. gattii. Clinicians outside the outbreak-affected areas should be aware of locally acquired C. gattii infection and its varied signs and symptoms.
- Subjects :
- Adult
Male
Microbiology (medical)
Adolescent
Genotype
Epidemiology
Pacific Northwest
Cryptococcus
lcsh:Medicine
Pulmonary disease
lcsh:Infectious and parasitic diseases
Disease Outbreaks
Young Adult
CME
parasitic diseases
medicine
pneumonia
Humans
lcsh:RC109-216
Young adult
Cryptococcus gattii
Phylogeny
Aged
Aged, 80 and over
Lung Diseases, Fungal
biology
gattii
Research
lcsh:R
meningitis
Outbreak
Cryptococcosis
Middle Aged
bacterial infections and mycoses
medicine.disease
biology.organism_classification
United States
Infectious Diseases
fungal
Immunology
Female
fungi
Pneumonia (non-human)
Meningitis
Demography
Subjects
Details
- ISSN :
- 10806059 and 10806040
- Volume :
- 19
- Database :
- OpenAIRE
- Journal :
- Emerging Infectious Diseases
- Accession number :
- edsair.doi.dedup.....7b8c04f23bd33a53641370b02207ab65